Mass spectrometry: System based analysis?
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12520%2F10%3A43888485" target="_blank" >RIV/60076658:12520/10:43888485 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.3182/20100707-3-BE-2012.0040" target="_blank" >http://dx.doi.org/10.3182/20100707-3-BE-2012.0040</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3182/20100707-3-BE-2012.0040" target="_blank" >10.3182/20100707-3-BE-2012.0040</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Mass spectrometry: System based analysis?
Popis výsledku v původním jazyce
Correct interpretation of measurements from Liquid Chromatography in tandem with Mass Spectrometry (LC-MS) is mostly affected by presented noise. Noise additions are produced not only by random errors (random noise) but also by influence of mobile phase(systemic noise, baseline) from Liquid chromatography. Sum of the noise and signal may produce false interpretation or hide the signal under reasonable level. The LC-MS data are complex and algorithms based only on filtering in chromatographic domain (Total Ion Current - TIC) nor only in individual mass spectra can not have performance as good as algorithms which incorporate information from both domains together. Generally, filtration using hard fixed threshold values are problematic. Its results are often inconsistent between runs, instrumentation and methods because the values from nearest threshold neighborhood may be easily miss-classi fied. We proposed a novel method based on system approach to LC-MS data analysis. Because the pre
Název v anglickém jazyce
Mass spectrometry: System based analysis?
Popis výsledku anglicky
Correct interpretation of measurements from Liquid Chromatography in tandem with Mass Spectrometry (LC-MS) is mostly affected by presented noise. Noise additions are produced not only by random errors (random noise) but also by influence of mobile phase(systemic noise, baseline) from Liquid chromatography. Sum of the noise and signal may produce false interpretation or hide the signal under reasonable level. The LC-MS data are complex and algorithms based only on filtering in chromatographic domain (Total Ion Current - TIC) nor only in individual mass spectra can not have performance as good as algorithms which incorporate information from both domains together. Generally, filtration using hard fixed threshold values are problematic. Its results are often inconsistent between runs, instrumentation and methods because the values from nearest threshold neighborhood may be easily miss-classi fied. We proposed a novel method based on system approach to LC-MS data analysis. Because the pre
Klasifikace
Druh
D - Stať ve sborníku
CEP obor
BD - Teorie informace
OECD FORD obor
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Návaznosti výsledku
Projekt
—
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2010
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název statě ve sborníku
IFAC Proceedings Volumes (IFAC-PapersOnline)
ISBN
978-3-902661-70-8
ISSN
1474-6670
e-ISSN
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Počet stran výsledku
6
Strana od-do
269-274
Název nakladatele
International Federation of Automatic Control (EIFAC)
Místo vydání
New York, USA
Místo konání akce
Leuven; Belgium
Datum konání akce
7. 6. 2010
Typ akce podle státní příslušnosti
WRD - Celosvětová akce
Kód UT WoS článku
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