Effects of Mercury on Oxidative Stress and Gene Expression of Potential Biomarkers in Larvae of the Chinese Rare Minnow Gobiocypris Rarus

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12520%2F14%3A43886785" target="_blank" >RIV/60076658:12520/14:43886785 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s00244-014-0034-6" target="_blank" >http://dx.doi.org/10.1007/s00244-014-0034-6</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00244-014-0034-6" target="_blank" >10.1007/s00244-014-0034-6</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Effects of Mercury on Oxidative Stress and Gene Expression of Potential Biomarkers in Larvae of the Chinese Rare Minnow Gobiocypris Rarus

Popis výsledku v původním jazyce

Mercury levels have increased in aquatic food webs throughout the world and can be found at toxic levels in some biota. However, the molecular mechanisms and effects of mercuric chloride (Hg2+) remain poorly understood. In the present study, antioxidantparameters (superoxide dismutase, catalase, glutathione peroxidase, and malondialdehyde)-as well as a series of gene expressions, including cortisol receptor (cr), Na+/K+-ATPase (aptase), and prolactin (prl) genes involved in ion-regulatory process, insulin-like growth factor I (igf1) and growth hormone (gh) related to growth rate, as well as heat shock protein70 (hsp70) and metallothionein (mt) used as physiological stress identification-were measured in whole body of Chinese rare minnow larvae (Gobiocypris rarus) after exposure to Hg2+ (0, 0.1, and 0.3 mg/L) for 4 days. Results show that oxidative stress was generated in fish exposed to Hg2+ and that the transcription levels of cr, atpase, gh, hsp70, and mt genes increased in a dose-d

Název v anglickém jazyce

Effects of Mercury on Oxidative Stress and Gene Expression of Potential Biomarkers in Larvae of the Chinese Rare Minnow Gobiocypris Rarus

Popis výsledku anglicky

Mercury levels have increased in aquatic food webs throughout the world and can be found at toxic levels in some biota. However, the molecular mechanisms and effects of mercuric chloride (Hg2+) remain poorly understood. In the present study, antioxidantparameters (superoxide dismutase, catalase, glutathione peroxidase, and malondialdehyde)-as well as a series of gene expressions, including cortisol receptor (cr), Na+/K+-ATPase (aptase), and prolactin (prl) genes involved in ion-regulatory process, insulin-like growth factor I (igf1) and growth hormone (gh) related to growth rate, as well as heat shock protein70 (hsp70) and metallothionein (mt) used as physiological stress identification-were measured in whole body of Chinese rare minnow larvae (Gobiocypris rarus) after exposure to Hg2+ (0, 0.1, and 0.3 mg/L) for 4 days. Results show that oxidative stress was generated in fish exposed to Hg2+ and that the transcription levels of cr, atpase, gh, hsp70, and mt genes increased in a dose-d

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GL - Rybářství

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Archives of Environmental Contamination and Toxicology

ISSN

0090-4341

e-ISSN

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Svazek periodika

67

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

7

Strana od-do

245-251

Kód UT WoS článku

000339008400011

EID výsledku v databázi Scopus

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