Simultaneous determination of 32 antibiotics in aquaculture products using LC-MS/MS

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12520%2F14%3A43886888" target="_blank" >RIV/60076658:12520/14:43886888 - isvavai.cz</a>

Výsledek na webu

<a href="http://link.springer.com/article/10.2478%2Fs11696-013-0428-3" target="_blank" >http://link.springer.com/article/10.2478%2Fs11696-013-0428-3</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2478/s11696-013-0428-3" target="_blank" >10.2478/s11696-013-0428-3</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Simultaneous determination of 32 antibiotics in aquaculture products using LC-MS/MS

Popis výsledku v původním jazyce

An analytical multiclass, multi-residue method for the determination of antibiotics in aquaculture products was developed and validated. A fast, cheap, and straightforward extraction procedure followed by liquid chromatography-tandem mass spectrometry analysis was proposed. This method covers 32 antibiotics of different classes, which are frequently used in aquaculture. Three different extraction procedures were compared, and the extraction with acetonitrile (0.1 vol. % formic acid) showed the best results. The selected extraction procedure was validated at four different fortification levels (10 mu g kg(-1), 25 mu g kg(-1), 50 mu g kg(-1), and 100 mu g kg(-1)). Recoveries of the tested antibiotics ranged from 70 % to 120 %, with the relative standarddeviation (RSD) of triplicates lower than 20 %. The limits of quantification (LOQ) ranged from 0.062 mu g kg(-1) to 4.6 mu g kg(-1), allowing for the analysis of trace levels of these antibiotics in aquaculture products. The method was ap

Název v anglickém jazyce

Simultaneous determination of 32 antibiotics in aquaculture products using LC-MS/MS

Popis výsledku anglicky

An analytical multiclass, multi-residue method for the determination of antibiotics in aquaculture products was developed and validated. A fast, cheap, and straightforward extraction procedure followed by liquid chromatography-tandem mass spectrometry analysis was proposed. This method covers 32 antibiotics of different classes, which are frequently used in aquaculture. Three different extraction procedures were compared, and the extraction with acetonitrile (0.1 vol. % formic acid) showed the best results. The selected extraction procedure was validated at four different fortification levels (10 mu g kg(-1), 25 mu g kg(-1), 50 mu g kg(-1), and 100 mu g kg(-1)). Recoveries of the tested antibiotics ranged from 70 % to 120 %, with the relative standarddeviation (RSD) of triplicates lower than 20 %. The limits of quantification (LOQ) ranged from 0.062 mu g kg(-1) to 4.6 mu g kg(-1), allowing for the analysis of trace levels of these antibiotics in aquaculture products. The method was ap

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

DJ - Znečištění a kontrola vody

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Chemical Papers

ISSN

0366-6352

e-ISSN

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Svazek periodika

68

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

PL - Polská republika

Počet stran výsledku

8

Strana od-do

29-36

Kód UT WoS článku

000324491200004

EID výsledku v databázi Scopus

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