The Flagellar Mechanics of Spermatozoa and its Regulation

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

The Flagellar Mechanics of Spermatozoa and its Regulation

Popis výsledku v původním jazyce

Motility is a characteristic function of the male gamete, which allows spermatozoa to actively reach and penetrate the female gamete in organisms with internal and external fertilization. Sperm motility is acquired under the control of many extrinsic and intrinsic factors and is based on the specialized structure of the sperm flagellum. An overview of how the sperm flagellum is organized and works to support cell motility is presented, with special focus on the molecular mechanisms and factors involved in the development and maintenance of sperm motility. Data obtained both in organisms with external fertilization, such as sea urchins, ascidians or fishes as well as those relying on internal fertilization, such as mammals, are critically analyzed. In most animal species, sperm motility is dependent on a long appendage called flagellum. Flagella are essential organelles found in most eukaryotic cells: their basic structure is the axoneme, built of a scaffold of microtubules and responsible for movement generation in an autonomous manner provided energy in the form of ATP is present. Beating of flagella allows movement, using thrust on the milieu surrounding sperm cells and is responsible of the translational drive of spermatozoa either in the fluid or by contact with structures cells or tissues.

Název v anglickém jazyce

The Flagellar Mechanics of Spermatozoa and its Regulation

Popis výsledku anglicky

Motility is a characteristic function of the male gamete, which allows spermatozoa to actively reach and penetrate the female gamete in organisms with internal and external fertilization. Sperm motility is acquired under the control of many extrinsic and intrinsic factors and is based on the specialized structure of the sperm flagellum. An overview of how the sperm flagellum is organized and works to support cell motility is presented, with special focus on the molecular mechanisms and factors involved in the development and maintenance of sperm motility. Data obtained both in organisms with external fertilization, such as sea urchins, ascidians or fishes as well as those relying on internal fertilization, such as mammals, are critically analyzed. In most animal species, sperm motility is dependent on a long appendage called flagellum. Flagella are essential organelles found in most eukaryotic cells: their basic structure is the axoneme, built of a scaffold of microtubules and responsible for movement generation in an autonomous manner provided energy in the form of ATP is present. Beating of flagella allows movement, using thrust on the milieu surrounding sperm cells and is responsible of the translational drive of spermatozoa either in the fluid or by contact with structures cells or tissues.

Druh

C - Kapitola v odborné knize

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Flagellar Mechanics and Sperm Guidance

ISBN

978-1-68108-129-8

Počet stran výsledku

132

Strana od-do

3-134

Počet stran knihy

432

Název nakladatele

Bentham Science Publishers Ltd.

Místo vydání

Sharjah

Kód UT WoS kapitoly

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