Adipokinetic hormones (AKHs) of sphingid Lepidoptera, including the identification of a second M. sexta AKH
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F12%3A00377574" target="_blank" >RIV/60077344:_____/12:00377574 - isvavai.cz</a>
Výsledek na webu
<a href="http://www.sciencedirect.com/science/article/pii/S0196978112000307" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0196978112000307</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.peptides.2012.01.009" target="_blank" >10.1016/j.peptides.2012.01.009</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Adipokinetic hormones (AKHs) of sphingid Lepidoptera, including the identification of a second M. sexta AKH
Popis výsledku v původním jazyce
The adipokinetic hormones (AKHs) from the corpora cardiaca (CC) of representative species from all three subfamilies of the Sphingidae (hawkmoths) were investigated using MALDI-TOF and LC?ESI MS. In addition to larvae and adults of M. sexta (subfamily: Sphinginae), adults from the following subfamilies were examined: Macroglossinae (large elephant hawkmoth, Deilephila elpenor), Smerinthinae (poplar hawkmoth, Laothoe populi and eyed hawkmoth, Smerinthus ocellata), and Sphinginae (death?s head hawkmoth, Acherontia atropos). All moths have the nonapeptide Manse-AKH (pELTFTSSGWamide) in their CC, together with a second AKH, which is identical in all species examined. It is a novel decapeptide AKH of pELTFSSGWGQamide (Manse-AKH-II). Sequence confirmation was obtained with synthetic Manse-AKH-II and with the native peptide. Manse-AKH-II has significant lipid-mobilizing activity. The potential implications of a second AKH are discussed in relation to putative receptor(s).
Název v anglickém jazyce
Adipokinetic hormones (AKHs) of sphingid Lepidoptera, including the identification of a second M. sexta AKH
Popis výsledku anglicky
The adipokinetic hormones (AKHs) from the corpora cardiaca (CC) of representative species from all three subfamilies of the Sphingidae (hawkmoths) were investigated using MALDI-TOF and LC?ESI MS. In addition to larvae and adults of M. sexta (subfamily: Sphinginae), adults from the following subfamilies were examined: Macroglossinae (large elephant hawkmoth, Deilephila elpenor), Smerinthinae (poplar hawkmoth, Laothoe populi and eyed hawkmoth, Smerinthus ocellata), and Sphinginae (death?s head hawkmoth, Acherontia atropos). All moths have the nonapeptide Manse-AKH (pELTFTSSGWamide) in their CC, together with a second AKH, which is identical in all species examined. It is a novel decapeptide AKH of pELTFSSGWGQamide (Manse-AKH-II). Sequence confirmation was obtained with synthetic Manse-AKH-II and with the native peptide. Manse-AKH-II has significant lipid-mobilizing activity. The potential implications of a second AKH are discussed in relation to putative receptor(s).
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
ED - Fyziologie
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/GAP206%2F10%2F2401" target="_blank" >GAP206/10/2401: Profilování metabolitů a potenciálních biomarkerů v moči pacientů s diagnostikovanou rakovinou prsu nebo prostaty</a><br>
Návaznosti
Z - Vyzkumny zamer (s odkazem do CEZ)
Ostatní
Rok uplatnění
2012
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Peptides
ISSN
0196-9781
e-ISSN
—
Svazek periodika
34
Číslo periodika v rámci svazku
1
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
7
Strana od-do
44-50
Kód UT WoS článku
000302851500007
EID výsledku v databázi Scopus
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