Spread of tetracycline resistance genes at a conventional dairy farm

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F15%3A00445408" target="_blank" >RIV/60077344:_____/15:00445408 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/67179843:_____/15:00445408

Výsledek na webu

<a href="http://dx.doi.org/10.3389/fmicb.2015.00536" target="_blank" >http://dx.doi.org/10.3389/fmicb.2015.00536</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3389/fmicb.2015.00536" target="_blank" >10.3389/fmicb.2015.00536</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Spread of tetracycline resistance genes at a conventional dairy farm

Popis výsledku v původním jazyce

The use of antibiotics in animal husbandry contributes to the worldwide problem of increasing antibiotic resistance in animal and human pathogens. Intensive animal production is considered an important source of antibiotic resistance genes released to the environment, while the contribution of smaller farms remains to be evaluated. Here we monitor the spread of tetracycline resistance (TC-r) genes at a middle-size conventional dairy farm, where chlortetracycline (CTC, as intrauterine suppository) is prophylactically used after each calving. Our study has shown that animals at the farm acquired the TC-r genes in their early age (1?2 weeks), likely due to colonization with TC-resistant bacteria from their mothers and/or the farm environment. The relativeabundance of the TC-r genes tet(W), tet(Q), and tet(M) in fresh excrements of calves was about 1?2 orders of magnitude higher compared to heifers and dairy cows, possibly due to the presence of antibiotic residues in milk fed to calves.

Název v anglickém jazyce

Spread of tetracycline resistance genes at a conventional dairy farm

Popis výsledku anglicky

The use of antibiotics in animal husbandry contributes to the worldwide problem of increasing antibiotic resistance in animal and human pathogens. Intensive animal production is considered an important source of antibiotic resistance genes released to the environment, while the contribution of smaller farms remains to be evaluated. Here we monitor the spread of tetracycline resistance (TC-r) genes at a middle-size conventional dairy farm, where chlortetracycline (CTC, as intrauterine suppository) is prophylactically used after each calving. Our study has shown that animals at the farm acquired the TC-r genes in their early age (1?2 weeks), likely due to colonization with TC-resistant bacteria from their mothers and/or the farm environment. The relativeabundance of the TC-r genes tet(W), tet(Q), and tet(M) in fresh excrements of calves was about 1?2 orders of magnitude higher compared to heifers and dairy cows, possibly due to the presence of antibiotic residues in milk fed to calves.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EE - Mikrobiologie, virologie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Frontiers in Microbiology

ISSN

1664-302X

e-ISSN

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Svazek periodika

6

Číslo periodika v rámci svazku

may

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

14

Strana od-do

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Kód UT WoS článku

000356305900001

EID výsledku v databázi Scopus

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