Pathology of Angiostrongylus cantonensis infection in two model avian hosts

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F21%3A00553175" target="_blank" >RIV/60077344:_____/21:00553175 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/62157124:16170/20:43878443 RIV/00216224:14310/21:00121028

Výsledek na webu

<a href="https://www.cambridge.org/core/journals/parasitology/article/abs/pathology-of-angiostrongylus-cantonensis-infection-in-two-model-avian-hosts/6C0EC93076345AF8658C5AA5A56AC562" target="_blank" >https://www.cambridge.org/core/journals/parasitology/article/abs/pathology-of-angiostrongylus-cantonensis-infection-in-two-model-avian-hosts/6C0EC93076345AF8658C5AA5A56AC562</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1017/S0031182020001869" target="_blank" >10.1017/S0031182020001869</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Pathology of Angiostrongylus cantonensis infection in two model avian hosts

Popis výsledku v původním jazyce

Angiostrongylus cantonensis causes severe neurological disorders in a wide range of warm-blooded animals, including several avian species. A laboratory isolate of A. cantonensis originating from French Polynesia, genotyped as clade 2, was used to assess the effect of experimental infection in chicken and Japanese quail. Low dose groups of birds were infected orally by 100 L3 larvae, high dose groups by 1500 L3 larvae and the birds in the third group were fed three infected snails, mimicking a natural infection. Clinical signs during the first week after infection, haematology, biochemistry, gross lesions and histology findings were used to assess the pathology of the infection. Some of the infected birds showed peripheral eosinophilia, while mild neurological signs were seen in others. No larvae were observed in serial sections of the central nervous system of infected birds 1 week after infection and no major gross lesions were observed during necropsy, histopathology did not reveal lesions directly attributable to A. cantonensis infection. Our results suggest that galliform birds are not highly susceptible to A. cantonensis infection and open a question of the importance of Galliformes in endemic areas as natural pest control, lowering the number of hosts carrying the infective larvae.

Název v anglickém jazyce

Pathology of Angiostrongylus cantonensis infection in two model avian hosts

Popis výsledku anglicky

Angiostrongylus cantonensis causes severe neurological disorders in a wide range of warm-blooded animals, including several avian species. A laboratory isolate of A. cantonensis originating from French Polynesia, genotyped as clade 2, was used to assess the effect of experimental infection in chicken and Japanese quail. Low dose groups of birds were infected orally by 100 L3 larvae, high dose groups by 1500 L3 larvae and the birds in the third group were fed three infected snails, mimicking a natural infection. Clinical signs during the first week after infection, haematology, biochemistry, gross lesions and histology findings were used to assess the pathology of the infection. Some of the infected birds showed peripheral eosinophilia, while mild neurological signs were seen in others. No larvae were observed in serial sections of the central nervous system of infected birds 1 week after infection and no major gross lesions were observed during necropsy, histopathology did not reveal lesions directly attributable to A. cantonensis infection. Our results suggest that galliform birds are not highly susceptible to A. cantonensis infection and open a question of the importance of Galliformes in endemic areas as natural pest control, lowering the number of hosts carrying the infective larvae.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

40301 - Veterinary science

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Parasitology

ISSN

0031-1820

e-ISSN

1469-8161

Svazek periodika

148

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

4

Strana od-do

174-177

Kód UT WoS článku

000618367600008

EID výsledku v databázi Scopus

2-s2.0-85092167289