Unique genetic structure of the human tapeworm Dibothriocephalus latus from the Alpine lakes region a successful adaptation?
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F22%3A00558635" target="_blank" >RIV/60077344:_____/22:00558635 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/60076658:12310/22:43904686
Výsledek na webu
<a href="https://www.cambridge.org/core/journals/parasitology/article/abs/unique-genetic-structure-of-the-human-tapeworm-dibothriocephalus-latus-from-the-alpine-lakes-region-a-successful-adaptation/FFBAE28A0916196BE62537759BD17CD5" target="_blank" >https://www.cambridge.org/core/journals/parasitology/article/abs/unique-genetic-structure-of-the-human-tapeworm-dibothriocephalus-latus-from-the-alpine-lakes-region-a-successful-adaptation/FFBAE28A0916196BE62537759BD17CD5</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1017/S0031182022000634" target="_blank" >10.1017/S0031182022000634</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Unique genetic structure of the human tapeworm Dibothriocephalus latus from the Alpine lakes region a successful adaptation?
Popis výsledku v původním jazyce
Dibothriocephalus latus is the most frequent causative agent of fish-borne zoonosis (diphyllobothriosis) in Europe, where it is currently circulating mainly in the Alpine lakes region (ALR) and Russia. Three mitochondrial genes (cox1, cob and nad3) and 6 microsatellite loci were analysed to determine how is the recently detected triploidy/parthenogenesis in tapeworms from ALR displayed at the DNA level. A geographically distant population from the Krasnoyarsk Reservoir in Russia (RU-KR) was analysed as a comparative population. One or 2 alleles of each microsatellite locus was detected in plerocercoids from RU-KR, corresponding to the microsatellite pattern of a diploid organism. In contrast, 1-3 alleles were observed in tapeworms from ALR, in accordance with their triploidy. The high diversity of mitochondrial haplotypes in D. latus from RU-KR implied an original and relatively stable population, but the identical structure of mitochondrial genes of tapeworms from ALR was probably a consequence of a bottleneck typical of introduced populations. These results indicated that the diploid/sexually reproducing population from RU-KR was ancestral, located within the centre of the distribution of the species, and the triploid/parthenogenetically reproducing subalpine population was at the margin of the distribution. The current study revealed the allelic structure of the microsatellite loci in the triploid tapeworm for the first time.
Název v anglickém jazyce
Unique genetic structure of the human tapeworm Dibothriocephalus latus from the Alpine lakes region a successful adaptation?
Popis výsledku anglicky
Dibothriocephalus latus is the most frequent causative agent of fish-borne zoonosis (diphyllobothriosis) in Europe, where it is currently circulating mainly in the Alpine lakes region (ALR) and Russia. Three mitochondrial genes (cox1, cob and nad3) and 6 microsatellite loci were analysed to determine how is the recently detected triploidy/parthenogenesis in tapeworms from ALR displayed at the DNA level. A geographically distant population from the Krasnoyarsk Reservoir in Russia (RU-KR) was analysed as a comparative population. One or 2 alleles of each microsatellite locus was detected in plerocercoids from RU-KR, corresponding to the microsatellite pattern of a diploid organism. In contrast, 1-3 alleles were observed in tapeworms from ALR, in accordance with their triploidy. The high diversity of mitochondrial haplotypes in D. latus from RU-KR implied an original and relatively stable population, but the identical structure of mitochondrial genes of tapeworms from ALR was probably a consequence of a bottleneck typical of introduced populations. These results indicated that the diploid/sexually reproducing population from RU-KR was ancestral, located within the centre of the distribution of the species, and the triploid/parthenogenetically reproducing subalpine population was at the margin of the distribution. The current study revealed the allelic structure of the microsatellite loci in the triploid tapeworm for the first time.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
30310 - Parasitology
Návaznosti výsledku
Projekt
—
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2022
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Parasitology
ISSN
0031-1820
e-ISSN
1469-8161
Svazek periodika
149
Číslo periodika v rámci svazku
8
Stát vydavatele periodika
GB - Spojené království Velké Británie a Severního Irska
Počet stran výsledku
13
Strana od-do
1106-1118
Kód UT WoS článku
000805016900001
EID výsledku v databázi Scopus
2-s2.0-85130567068