Approaches to quantify and manipulate insect hormone signals

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F25%3A00644677" target="_blank" >RIV/60077344:_____/25:00644677 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60076658:12310/25:43910249

Výsledek na webu

<a href="https://doi.org/10.1016/j.cois.2025.101425" target="_blank" >https://doi.org/10.1016/j.cois.2025.101425</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.cois.2025.101425" target="_blank" >10.1016/j.cois.2025.101425</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Approaches to quantify and manipulate insect hormone signals

Popis výsledku v původním jazyce

Hormones play a decisive role in many aspects of insect biology. To study processes controlled by hormones, one needs methods to identify and quantify hormone titers and tools to enhance or suppress hormonal signaling experimentally. In this review, we focus on the key lipidic insect hormones, the juvenile hormones (JHs), and the ecdysteroids. The lipophilic nature of JH and ecdysteroids in combination with their low endogenous titers makes handling and quantification challenging but feasible owing to the improvement of analytical detection methods. Chemical and genetic approaches to modulate hormonal homeostasis have been developed based on knowledge of hormone biosynthetic and biodegrading enzymes, transporters, and receptors and enabled by advances in reverse genetics techniques. Here, we overview contemporary methods available to detect and quantify JHs and ecdysteroids from insect samples and to manipulate endocrine homeostasis.

Název v anglickém jazyce

Approaches to quantify and manipulate insect hormone signals

Popis výsledku anglicky

Hormones play a decisive role in many aspects of insect biology. To study processes controlled by hormones, one needs methods to identify and quantify hormone titers and tools to enhance or suppress hormonal signaling experimentally. In this review, we focus on the key lipidic insect hormones, the juvenile hormones (JHs), and the ecdysteroids. The lipophilic nature of JH and ecdysteroids in combination with their low endogenous titers makes handling and quantification challenging but feasible owing to the improvement of analytical detection methods. Chemical and genetic approaches to modulate hormonal homeostasis have been developed based on knowledge of hormone biosynthetic and biodegrading enzymes, transporters, and receptors and enabled by advances in reverse genetics techniques. Here, we overview contemporary methods available to detect and quantify JHs and ecdysteroids from insect samples and to manipulate endocrine homeostasis.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10608 - Biochemistry and molecular biology

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Current Opinion in Insect Science

ISSN

2214-5745

e-ISSN

2214-5753

Svazek periodika

72

Číslo periodika v rámci svazku

DEC

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

9

Strana od-do

101425

Kód UT WoS článku

001591296000001

EID výsledku v databázi Scopus

2-s2.0-105013637892