New lytic and new temperate Staphylococcus hyicus phages
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F25%3A00646270" target="_blank" >RIV/60077344:_____/25:00646270 - isvavai.cz</a>
Výsledek na webu
<a href="https://link.springer.com/article/10.1007/s11262-025-02151-5" target="_blank" >https://link.springer.com/article/10.1007/s11262-025-02151-5</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s11262-025-02151-5" target="_blank" >10.1007/s11262-025-02151-5</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
New lytic and new temperate Staphylococcus hyicus phages
Popis výsledku v původním jazyce
A novel lytic phage with a broad host range was isolated from pig faeces and the complete genome was subsequently sequenced. The phage was found to lyse Staphylococcus hyicus, S. pseudintermedius, S. schleiferi and S. warneri, generating approximately 27 PFU per infected S. hyicus cell. The phage has an isometric head of 42 +/- 2 nm in diameter and a noncontractile tail of 114 +/- 9 nm long. The genome is 53,660 bp in size and consists of 79 predicted ORFs and one tRNAArg gene. The phage has been classified within the Caudoviricetes, specifically the Chaseviridae family. Its broad host range and absence of harmful genes make it suitable for use in phage therapy. In addition, a novel temperate phage was discovered that was spontaneously released from a S. hyicus isolate Pel11 from a pig with exudative epidermitis. This novel temperate phage differs from the known temperate phages in S. hyicus strains NCTC10350, MM2101 or 83/7-1B, representing a novel pathogenicity element in the S. hyicus genome.
Název v anglickém jazyce
New lytic and new temperate Staphylococcus hyicus phages
Popis výsledku anglicky
A novel lytic phage with a broad host range was isolated from pig faeces and the complete genome was subsequently sequenced. The phage was found to lyse Staphylococcus hyicus, S. pseudintermedius, S. schleiferi and S. warneri, generating approximately 27 PFU per infected S. hyicus cell. The phage has an isometric head of 42 +/- 2 nm in diameter and a noncontractile tail of 114 +/- 9 nm long. The genome is 53,660 bp in size and consists of 79 predicted ORFs and one tRNAArg gene. The phage has been classified within the Caudoviricetes, specifically the Chaseviridae family. Its broad host range and absence of harmful genes make it suitable for use in phage therapy. In addition, a novel temperate phage was discovered that was spontaneously released from a S. hyicus isolate Pel11 from a pig with exudative epidermitis. This novel temperate phage differs from the known temperate phages in S. hyicus strains NCTC10350, MM2101 or 83/7-1B, representing a novel pathogenicity element in the S. hyicus genome.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
10607 - Virology
Návaznosti výsledku
Projekt
Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2025
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Virus Genes
ISSN
0920-8569
e-ISSN
1572-994X
Svazek periodika
61
Číslo periodika v rámci svazku
3
Stát vydavatele periodika
DE - Spolková republika Německo
Počet stran výsledku
3
Strana od-do
377-380
Kód UT WoS článku
001444588600001
EID výsledku v databázi Scopus
2-s2.0-105000167430