Innate immune NK celss and their role in HIV and SIV infection

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F10%3A00002245" target="_blank" >RIV/60162694:G44__/10:00002245 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Innate immune NK celss and their role in HIV and SIV infection

Popis výsledku v původním jazyce

The findings that early events during HIV-1and SIV infection of Asian macaques dictate the levels of viremia and rate of disease progression prior to the establishment of mature and effective adaptive imine responses strongly suggest en important role for ikate imine mechanisms. In addition, the fact that the major target of HIV and Siv during this period of acute infection is the gastrointestinal tissue suggests that whatever role the ikate imine systém plays must ether directly and/or indirectly focusonon the GI tract. The studies summarized include our current understanding of the phenotypic heterogenity, the stative functions ascribed to the subsets, the maturation/differentiation of NK cells, the mechanisms by which thein fiction is mediated and regulated, the studies these NK-cell subsets, which a focus on killer cell imunoglobulin like receptors (KIRs) in nonhuman primates and humus, how HIV and SIV infection affects these NK cell in vivo

Název v anglickém jazyce

Innate immune NK celss and their role in HIV and SIV infection

Popis výsledku anglicky

The findings that early events during HIV-1and SIV infection of Asian macaques dictate the levels of viremia and rate of disease progression prior to the establishment of mature and effective adaptive imine responses strongly suggest en important role for ikate imine mechanisms. In addition, the fact that the major target of HIV and Siv during this period of acute infection is the gastrointestinal tissue suggests that whatever role the ikate imine systém plays must ether directly and/or indirectly focusonon the GI tract. The studies summarized include our current understanding of the phenotypic heterogenity, the stative functions ascribed to the subsets, the maturation/differentiation of NK cells, the mechanisms by which thein fiction is mediated and regulated, the studies these NK-cell subsets, which a focus on killer cell imunoglobulin like receptors (KIRs) in nonhuman primates and humus, how HIV and SIV infection affects these NK cell in vivo

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EC - Imunologie

OECD FORD obor

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Projekt

<a href="/cs/project/GAP304%2F10%2F1161" target="_blank" >GAP304/10/1161: Role buněčných proteinů asociovaných s viry v patogenezi dysfunkce T lymfocytů</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2010

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

HIV Therapy

ISSN

1758-4310

e-ISSN

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Svazek periodika

4

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

22

Strana od-do

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Kód UT WoS článku

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EID výsledku v databázi Scopus

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