The role of B cells in intracellular bacterial pathogen infections
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F13%3A43874904" target="_blank" >RIV/60162694:G44__/13:43874904 - isvavai.cz</a>
Výsledek na webu
<a href="https://www.novapublishers.com/catalog/product_info.php?cPath=23_131_162&products_id=39506" target="_blank" >https://www.novapublishers.com/catalog/product_info.php?cPath=23_131_162&products_id=39506</a>
DOI - Digital Object Identifier
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Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
The role of B cells in intracellular bacterial pathogen infections
Popis výsledku v původním jazyce
The protective immune response against facultative intracellular bacterial pathogens, as are Brucella melitensis, Francisella tularensis, Listeria monocytogenes, or Salmonella sp. requires concerted action of activated immunocompetent cells. In this respect the dominant role has been attributed to activated T lymphocyte subpopulations and/or activated macrophages. Recently become clear that the B cell subsets are the equivalent partner of T cells during the induction, regulation and expression phases ofthe immune response against intracellular bacteria. They express their functions by both antibody-dependent and by antibody-independent mechanisms. B cells are able to internalize bacteria through their BCR, extract the antigens from the non-internalizable particles, and are able due to the cross-presentation process activate CD4+ as well as CD8+ T cells. Through the dichotomy of the recognition of bacterial targets by BCR or TLR and by the production of sets of cytokines the B cells re
Název v anglickém jazyce
The role of B cells in intracellular bacterial pathogen infections
Popis výsledku anglicky
The protective immune response against facultative intracellular bacterial pathogens, as are Brucella melitensis, Francisella tularensis, Listeria monocytogenes, or Salmonella sp. requires concerted action of activated immunocompetent cells. In this respect the dominant role has been attributed to activated T lymphocyte subpopulations and/or activated macrophages. Recently become clear that the B cell subsets are the equivalent partner of T cells during the induction, regulation and expression phases ofthe immune response against intracellular bacteria. They express their functions by both antibody-dependent and by antibody-independent mechanisms. B cells are able to internalize bacteria through their BCR, extract the antigens from the non-internalizable particles, and are able due to the cross-presentation process activate CD4+ as well as CD8+ T cells. Through the dichotomy of the recognition of bacterial targets by BCR or TLR and by the production of sets of cytokines the B cells re
Klasifikace
Druh
C - Kapitola v odborné knize
CEP obor
EC - Imunologie
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/GAP302%2F11%2F1631" target="_blank" >GAP302/11/1631: Úloha B buněk v přirozené a adaptivní imunitní odpovědi proti infekci Francisella tularensis u myší.</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2013
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název knihy nebo sborníku
B Cells: Molecular Biology, Developmental Origin and Impact on the Immune System
ISBN
978-1-62808-541-9
Počet stran výsledku
44
Strana od-do
1-44
Počet stran knihy
119
Název nakladatele
Nova Science Publishers - NY
Místo vydání
New York
Kód UT WoS kapitoly
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