Glycated Hemoglobin and Methods for Its Point of Care Testing

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F21%3A00556884" target="_blank" >RIV/60162694:G44__/21:00556884 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.mdpi.com/2079-6374/11/3/70" target="_blank" >https://www.mdpi.com/2079-6374/11/3/70</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/bios11030070" target="_blank" >10.3390/bios11030070</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Glycated Hemoglobin and Methods for Its Point of Care Testing

Popis výsledku v původním jazyce

Glycated hemoglobin (HbA(1c)) is a product of the spontaneous reaction between hemoglobin and elevated glucose levels in the blood. It is included among the so-called advanced glycation end products, of which is the most important for the clinical diagnosis of diabetes mellitus, and it can serve as an alternative to glycemia measurement. Compared to the diagnosis of diabetes mellitus by glycemia, the HbA(1c) level is less influenced by a short-term problem with diabetes compensation. Mass spectroscopy and chromatographic techniques are among the standard methods of HbA(1c) level measurement. Compared to glycemia measurement, there is lack of simple methods for diabetes mellitus diagnosis by means of the HbA(1c) assay using a point-of-care test. This review article is focused on the surveying of facts about HbA(1c) and its importance in diabetes mellitus diagnosis, and surveying standard methods and new methods suitable for the HbA(1c) assay under point-of-care conditions. Various bioassays and biosensors are mentioned and their specifications are discussed.

Název v anglickém jazyce

Glycated Hemoglobin and Methods for Its Point of Care Testing

Popis výsledku anglicky

Glycated hemoglobin (HbA(1c)) is a product of the spontaneous reaction between hemoglobin and elevated glucose levels in the blood. It is included among the so-called advanced glycation end products, of which is the most important for the clinical diagnosis of diabetes mellitus, and it can serve as an alternative to glycemia measurement. Compared to the diagnosis of diabetes mellitus by glycemia, the HbA(1c) level is less influenced by a short-term problem with diabetes compensation. Mass spectroscopy and chromatographic techniques are among the standard methods of HbA(1c) level measurement. Compared to glycemia measurement, there is lack of simple methods for diabetes mellitus diagnosis by means of the HbA(1c) assay using a point-of-care test. This review article is focused on the surveying of facts about HbA(1c) and its importance in diabetes mellitus diagnosis, and surveying standard methods and new methods suitable for the HbA(1c) assay under point-of-care conditions. Various bioassays and biosensors are mentioned and their specifications are discussed.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10406 - Analytical chemistry

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biosensors-Basel

ISSN

2079-6374

e-ISSN

2079-6374

Svazek periodika

11

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

12

Strana od-do

70

Kód UT WoS článku

000633395200001

EID výsledku v databázi Scopus

2-s2.0-85103862731