Fluorometric and Colorimetric Biosensors for the Assay of Cholinesterase Inhibitors

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F26%3A00564518" target="_blank" >RIV/60162694:G44__/26:00564518 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.mdpi.com/1424-8220/25/9/2674" target="_blank" >https://www.mdpi.com/1424-8220/25/9/2674</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/s25092674" target="_blank" >10.3390/s25092674</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Fluorometric and Colorimetric Biosensors for the Assay of Cholinesterase Inhibitors

Popis výsledku v původním jazyce

Cholinesterases, specifically acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), play critical roles in neurotransmission and are key targets for inhibitors with therapeutic and toxicological significance. This review focuses on the development and application of fluorometric and colorimetric biosensors for the detection of cholinesterase inhibitors. These biosensors take advantage of the unique properties of AChE and BChE to provide sensitive and selective detection methods essential for environmental monitoring, food safety, and clinical diagnostics. Recent advances in assay techniques, including the use of gold nanoparticles, pseudoperoxidase nanomaterials, and innovative enzyme-substrate interactions, are highlighted. This review also discusses challenges and future directions for optimizing these biosensors for practical applications, emphasizing their potential to enhance public health and safety.

Název v anglickém jazyce

Fluorometric and Colorimetric Biosensors for the Assay of Cholinesterase Inhibitors

Popis výsledku anglicky

Cholinesterases, specifically acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), play critical roles in neurotransmission and are key targets for inhibitors with therapeutic and toxicological significance. This review focuses on the development and application of fluorometric and colorimetric biosensors for the detection of cholinesterase inhibitors. These biosensors take advantage of the unique properties of AChE and BChE to provide sensitive and selective detection methods essential for environmental monitoring, food safety, and clinical diagnostics. Recent advances in assay techniques, including the use of gold nanoparticles, pseudoperoxidase nanomaterials, and innovative enzyme-substrate interactions, are highlighted. This review also discusses challenges and future directions for optimizing these biosensors for practical applications, emphasizing their potential to enhance public health and safety.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10406 - Analytical chemistry

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

SENSORS

ISSN

—

e-ISSN

1424-8220

Svazek periodika

25

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

17

Strana od-do

2674

Kód UT WoS článku

001486747800001

EID výsledku v databázi Scopus

2-s2.0-105004908610