ANALYSIS OF NERVE AGENTS THROUGH A MODIFIED METHOD OF CHOLINESTERASE ASSESSMENT USING ARTIFICIAL NEURONAL NETWORKS

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG45__%2F17%3A00534326" target="_blank" >RIV/60162694:G45__/17:00534326 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.mmsl.cz/pdfs/mms/2017/03/02.pdf" target="_blank" >https://www.mmsl.cz/pdfs/mms/2017/03/02.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

ANALYSIS OF NERVE AGENTS THROUGH A MODIFIED METHOD OF CHOLINESTERASE ASSESSMENT USING ARTIFICIAL NEURONAL NETWORKS

Popis výsledku v původním jazyce

A simple colorimetric biosensor, which uses the modified Ellman's reaction, enables selective analysis of nerve agents based on a different ability of bispyridinium oximes to reactivate enzyme-inhibitor complexes in the phase before dealkylation. The analysis was made based on spectral data of reflectance of the surface of a cotton cloth reaction zone of biosensor with immobilized and stabilized enzyme after inhibition and subsequent reactivation. The evaluation of measured data was made based on a method of artificial neuronal networks. The individual inhibitors from the groups of three nerve agents were identified: sarin, soman,tabun, cyclosarin, agent VX and its Russian analogue, R-33.

Název v anglickém jazyce

ANALYSIS OF NERVE AGENTS THROUGH A MODIFIED METHOD OF CHOLINESTERASE ASSESSMENT USING ARTIFICIAL NEURONAL NETWORKS

Popis výsledku anglicky

A simple colorimetric biosensor, which uses the modified Ellman's reaction, enables selective analysis of nerve agents based on a different ability of bispyridinium oximes to reactivate enzyme-inhibitor complexes in the phase before dealkylation. The analysis was made based on spectral data of reflectance of the surface of a cotton cloth reaction zone of biosensor with immobilized and stabilized enzyme after inhibition and subsequent reactivation. The evaluation of measured data was made based on a method of artificial neuronal networks. The individual inhibitors from the groups of three nerve agents were identified: sarin, soman,tabun, cyclosarin, agent VX and its Russian analogue, R-33.

Druh

J_ost - Ostatní články v recenzovaných periodicích

CEP obor

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OECD FORD obor

50902 - Social sciences, interdisciplinary

Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Military Medical Science Letters

ISSN

0372-7025

e-ISSN

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Svazek periodika

86

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

8

Strana od-do

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Kód UT WoS článku

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EID výsledku v databázi Scopus

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