Úloha oxidu dusnatého při partenogenetické aktivaci prasečích oocytů - review

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F07%3A23405" target="_blank" >RIV/60460709:41210/07:23405 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00027014:_____/07:#0000483

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

The role of nitric oxide in parthenogenetic activation of pig oocytes: A review

Popis výsledku v původním jazyce

Parthenogenetic activation of mammalian oocytes with the help of artificial stimuli is commonly applied in various reproductive biotechniques. e.g. cloning using nuclear transfer. For this reason, many studies focus on oocyte activation in vitro. Recently we have described activation of pig oocytes using nitric oxide. This activating stimulus is very specific in many aspects. However, it does not provide an adequate stimulus for parthenogenetic development. It was shown, that nitric oxide stimulates some signaling pathways which are inactive in conventional treatments for parthenogenetic activation, e.g. the cGMP-dependent signaling cascade. On the other hand, nitric oxide does not stimulate some signaling pathways involved in oocyte activation after calcium ionophore, e.g. the PKC signaling cascade. The aim of this review is to characterize the complex processes induced in oocytes after treatment with nitric oxide. Perspectives for further research and the application of nitric oxide

Název v anglickém jazyce

The role of nitric oxide in parthenogenetic activation of pig oocytes: A review

Popis výsledku anglicky

Parthenogenetic activation of mammalian oocytes with the help of artificial stimuli is commonly applied in various reproductive biotechniques. e.g. cloning using nuclear transfer. For this reason, many studies focus on oocyte activation in vitro. Recently we have described activation of pig oocytes using nitric oxide. This activating stimulus is very specific in many aspects. However, it does not provide an adequate stimulus for parthenogenetic development. It was shown, that nitric oxide stimulates some signaling pathways which are inactive in conventional treatments for parthenogenetic activation, e.g. the cGMP-dependent signaling cascade. On the other hand, nitric oxide does not stimulate some signaling pathways involved in oocyte activation after calcium ionophore, e.g. the PKC signaling cascade. The aim of this review is to characterize the complex processes induced in oocytes after treatment with nitric oxide. Perspectives for further research and the application of nitric oxide

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GG - Chov hospodářských zvířat

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2007

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Czech Journal of Animal Science

ISSN

1212-1819

e-ISSN

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Svazek periodika

52

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

15

Strana od-do

363-377

Kód UT WoS článku

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EID výsledku v databázi Scopus

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