Prooxidative effect of bisphenol S on porcine oocytes meiotic maturation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F18%3A78340" target="_blank" >RIV/60460709:41210/18:78340 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Prooxidative effect of bisphenol S on porcine oocytes meiotic maturation

Popis výsledku v původním jazyce

Many substances introduced to the environment exert endocrine disrupting effects and negatively affect human and animal reproduction. Plasticizers bisphenols belongs to a group of the most studied endocrine disruptors. However, the effects of bisphenol S on reproduction is not well characterized. It is known that some endocrine disruptors can induce in cells oxidative stress. The aim of our study was to test the hypothesis that BPS induces oxidative stress through ROS production in porcine oocytes during their meiotic maturation. Maturing oocytes were cultured in the presence of 300 nM and 30 uM of BPS, and levels of ROS in oocytes after 24 and 48 hours of cultivation were evaluated. Both concentration of BPS statistically significantly increased ROS production after cultivation. The experiments confirmed that BPS influences ROS production and induces oxidative stress during porcine oocytes meiotic maturation

Název v anglickém jazyce

Prooxidative effect of bisphenol S on porcine oocytes meiotic maturation

Popis výsledku anglicky

Many substances introduced to the environment exert endocrine disrupting effects and negatively affect human and animal reproduction. Plasticizers bisphenols belongs to a group of the most studied endocrine disruptors. However, the effects of bisphenol S on reproduction is not well characterized. It is known that some endocrine disruptors can induce in cells oxidative stress. The aim of our study was to test the hypothesis that BPS induces oxidative stress through ROS production in porcine oocytes during their meiotic maturation. Maturing oocytes were cultured in the presence of 300 nM and 30 uM of BPS, and levels of ROS in oocytes after 24 and 48 hours of cultivation were evaluated. Both concentration of BPS statistically significantly increased ROS production after cultivation. The experiments confirmed that BPS influences ROS production and induces oxidative stress during porcine oocytes meiotic maturation

Druh

D - Stať ve sborníku

CEP obor

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OECD FORD obor

10604 - Reproductive biology (medical aspects to be 3)

Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

10th Workshop on biodiversity, Jevany

ISBN

978-80-213-2910-2

ISSN

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e-ISSN

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Počet stran výsledku

4

Strana od-do

28-31

Název nakladatele

neuvedeno

Místo vydání

Praha

Místo konání akce

Jevany

Datum konání akce

10. 7. 2018

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

000464895800006