Outstanding insecticidal activity and sublethal effects of Carlina acaulis root essential oil on the housefly, Musca domestica, with insights on its toxicity on human cells

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F20%3A82394" target="_blank" >RIV/60460709:41210/20:82394 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00027006:_____/20:10149658

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0278691519308270?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0278691519308270?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.fct.2019.111037" target="_blank" >10.1016/j.fct.2019.111037</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Outstanding insecticidal activity and sublethal effects of Carlina acaulis root essential oil on the housefly, Musca domestica, with insights on its toxicity on human cells

Popis výsledku v původním jazyce

Carlina acaulis (Compositae) is traditionally used for food and medicinal purposes in central and southern Europe. Its root essential oil (EO), mainly composed by carlina oxide, is included in the BELFRIT botanical list of food supplements. It is also recognized as a potent mosquito larvicide. It is matter of concern whether this EO could be endowed with intrinsic toxicity to limit its use on a food level. Focusing on the insecticidal activity of this EO, we investigated the acute toxicity and sublethal effects on Musca domestica. In topical assays, the EO was extremely effective (LD50 = 2,74 and 5,96 mu g fly(-1), on males and females, respectively). The exposure to a sublethal dose (LD30) led to significant reductions of female longevity (LT50 = 6,7-9,0 days vs. control LT50 = 12,9-13,7 days). Treated females laid 2,5 times fewer eggs over control ones. F-1 vitality decreased: F-1 larvae and pupae showed high mortality, 2-4-fold higher over the control. The EO also showed high cytotoxicity on norma

Název v anglickém jazyce

Outstanding insecticidal activity and sublethal effects of Carlina acaulis root essential oil on the housefly, Musca domestica, with insights on its toxicity on human cells

Popis výsledku anglicky

Carlina acaulis (Compositae) is traditionally used for food and medicinal purposes in central and southern Europe. Its root essential oil (EO), mainly composed by carlina oxide, is included in the BELFRIT botanical list of food supplements. It is also recognized as a potent mosquito larvicide. It is matter of concern whether this EO could be endowed with intrinsic toxicity to limit its use on a food level. Focusing on the insecticidal activity of this EO, we investigated the acute toxicity and sublethal effects on Musca domestica. In topical assays, the EO was extremely effective (LD50 = 2,74 and 5,96 mu g fly(-1), on males and females, respectively). The exposure to a sublethal dose (LD30) led to significant reductions of female longevity (LT50 = 6,7-9,0 days vs. control LT50 = 12,9-13,7 days). Treated females laid 2,5 times fewer eggs over control ones. F-1 vitality decreased: F-1 larvae and pupae showed high mortality, 2-4-fold higher over the control. The EO also showed high cytotoxicity on norma

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

40106 - Agronomy, plant breeding and plant protection; (Agricultural biotechnology to be 4.4)

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

FOOD AND CHEMICAL TOXICOLOGY

ISSN

0278-6915

e-ISSN

1873-6351

Svazek periodika

136

Číslo periodika v rámci svazku

february

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

7

Strana od-do

1-7

Kód UT WoS článku

000514015300045

EID výsledku v databázi Scopus

2-s2.0-85076862046