NMR-based metabolomics as a significant tool for human nutritional research and health applications

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F23%3A96416" target="_blank" >RIV/60460709:41210/23:96416 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S221242922300189X?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S221242922300189X?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.fbio.2023.102538" target="_blank" >10.1016/j.fbio.2023.102538</a>

Jazyk výsledku

angličtina

Název v původním jazyce

NMR-based metabolomics as a significant tool for human nutritional research and health applications

Popis výsledku v původním jazyce

Metabolomics is one of the most reliable and widely used approaches to reveal the identity of a variety of bioactive metabolites. It is referred to as ‘Foodomics’ in food science and as ‘Nutrimetabolomics’ in nutrition. Nutrimetabolomics has been effectively used in nutritional sciences for intervention studies, identification of dietary biomarkers, and to study the role of metabolomics phenotyping in personalized nutrition for diet-related disorders, such as type 2 diabetes, obesity, metabolic syndrome, and prediabetes. NMR-based nutrimetabolomics has been preferred over other approaches due to its reliability, sensitivity, reproducibility, and specificity in detecting metabolites relating to human nutrition and metabolic disorders. Clinical samples such as blood, urine, and faeces could be analyzed for specific biomarkers involving NMR spectroscopic investigation followed by chemometric analysis. In this review, we have focused on NMR-based nutrimetabolomics strategies and their role in identifying dietary and disease-related biomarkers of significance to human nutrition and health. Moreover, this NMR-based metabolomics can play a significant role in determining, understanding, and regulating metabolites involved in the multidimensional and complex area of functional foods and diet-related metabolic diseases. This will disclose the application of NMR nutrimetabolomics in advanced precision and personalized nutrition, food authentication, and diet-oriented disease management systems.

Název v anglickém jazyce

NMR-based metabolomics as a significant tool for human nutritional research and health applications

Popis výsledku anglicky

Metabolomics is one of the most reliable and widely used approaches to reveal the identity of a variety of bioactive metabolites. It is referred to as ‘Foodomics’ in food science and as ‘Nutrimetabolomics’ in nutrition. Nutrimetabolomics has been effectively used in nutritional sciences for intervention studies, identification of dietary biomarkers, and to study the role of metabolomics phenotyping in personalized nutrition for diet-related disorders, such as type 2 diabetes, obesity, metabolic syndrome, and prediabetes. NMR-based nutrimetabolomics has been preferred over other approaches due to its reliability, sensitivity, reproducibility, and specificity in detecting metabolites relating to human nutrition and metabolic disorders. Clinical samples such as blood, urine, and faeces could be analyzed for specific biomarkers involving NMR spectroscopic investigation followed by chemometric analysis. In this review, we have focused on NMR-based nutrimetabolomics strategies and their role in identifying dietary and disease-related biomarkers of significance to human nutrition and health. Moreover, this NMR-based metabolomics can play a significant role in determining, understanding, and regulating metabolites involved in the multidimensional and complex area of functional foods and diet-related metabolic diseases. This will disclose the application of NMR nutrimetabolomics in advanced precision and personalized nutrition, food authentication, and diet-oriented disease management systems.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30308 - Nutrition, Dietetics

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Food Bioscience a Separations

ISSN

2212-4292

e-ISSN

2212-4292

Svazek periodika

53

Číslo periodika v rámci svazku

102538

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

13

Strana od-do

102538-102551

Kód UT WoS článku

000954918300001

EID výsledku v databázi Scopus

2-s2.0-85149465446