Exploring the chemical composition and biological effects of four Salvia hybrids: an innovative perspective on functional yields

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41320%2F24%3A100377" target="_blank" >RIV/60460709:41320/24:100377 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1002/efd2.70012" target="_blank" >http://dx.doi.org/10.1002/efd2.70012</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/efd2.70012" target="_blank" >10.1002/efd2.70012</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Exploring the chemical composition and biological effects of four Salvia hybrids: an innovative perspective on functional yields

Popis výsledku v původním jazyce

Genus Salvia is considered one of the largest genera of family Lamiaceae with many recorded species and hybrids of valuable biological importance. This study involved the phytochemical characterization of four Salvia hybrids (KNM23 (S. fructicosa x S. officinalis), KNM101 (S. aramiensis x S. officinalis), KNM5 (S. aramiensis x S. officinalis) and KNM12 (S. fructicosa x S. officinalis)) through measuring their total phenolic content (TPC) and total flavonoid content (TFC) together with profiling through UPLC/MSn analysis followed by investigation of their antioxidant activities and enzyme inhibitory potential through different techniques. Hybrid KNM23 presented significantly high concentration of both phenolic and flavonoid, displaying a TPC of 92.10 mg GAE/g and a TFC of 50.85 mg RE/g. The UPLC/MSn profiling resulted in the tentative identification of one hundred eighty components from different phytochemical classes mainly flavonoids, phenolic acids, phenyl propanoids, tannins and many others. The antioxidant assay showed that hybrid KNM23, a hybrid of S. fruticosa and S. officinalis, exhibited the highest antioxidant activity in the DPPH, ABTS, and PBD assays, measuring 436.38 mmol TE/g, 543.65 mmol TE/g, and 3.20 mmol TE/g, respectively. KNM23 and KNM12 showed no inhibition of AChE and alpha-glucosidase. However, KMN12 demonstrated highest BChE and tyrosinase 2.57 mg GALAE/g and 12.91 mg KAE/g, respectively. Our results suggest that the Salvia hybrids can be considered as natural sources of bioactive compounds in the development of health-promoting applications.

Název v anglickém jazyce

Exploring the chemical composition and biological effects of four Salvia hybrids: an innovative perspective on functional yields

Popis výsledku anglicky

Genus Salvia is considered one of the largest genera of family Lamiaceae with many recorded species and hybrids of valuable biological importance. This study involved the phytochemical characterization of four Salvia hybrids (KNM23 (S. fructicosa x S. officinalis), KNM101 (S. aramiensis x S. officinalis), KNM5 (S. aramiensis x S. officinalis) and KNM12 (S. fructicosa x S. officinalis)) through measuring their total phenolic content (TPC) and total flavonoid content (TFC) together with profiling through UPLC/MSn analysis followed by investigation of their antioxidant activities and enzyme inhibitory potential through different techniques. Hybrid KNM23 presented significantly high concentration of both phenolic and flavonoid, displaying a TPC of 92.10 mg GAE/g and a TFC of 50.85 mg RE/g. The UPLC/MSn profiling resulted in the tentative identification of one hundred eighty components from different phytochemical classes mainly flavonoids, phenolic acids, phenyl propanoids, tannins and many others. The antioxidant assay showed that hybrid KNM23, a hybrid of S. fruticosa and S. officinalis, exhibited the highest antioxidant activity in the DPPH, ABTS, and PBD assays, measuring 436.38 mmol TE/g, 543.65 mmol TE/g, and 3.20 mmol TE/g, respectively. KNM23 and KNM12 showed no inhibition of AChE and alpha-glucosidase. However, KMN12 demonstrated highest BChE and tyrosinase 2.57 mg GALAE/g and 12.91 mg KAE/g, respectively. Our results suggest that the Salvia hybrids can be considered as natural sources of bioactive compounds in the development of health-promoting applications.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10511 - Environmental sciences (social aspects to be 5.7)

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Efood

ISSN

2666-3066

e-ISSN

2666-3066

Svazek periodika

5

Číslo periodika v rámci svazku

5.0

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

26

Strana od-do

1-26

Kód UT WoS článku

001330696200001

EID výsledku v databázi Scopus

2-s2.0-85206152801