Multiple In vitro biological effects of phenolic compounds from Morus alba root bark

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41330%2F20%3A82283" target="_blank" >RIV/60460709:41330/20:82283 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14160/20:00118192 RIV/62157124:16170/20:43878879

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/abs/pii/S0378874119337298?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S0378874119337298?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jep.2019.112296" target="_blank" >10.1016/j.jep.2019.112296</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Multiple In vitro biological effects of phenolic compounds from Morus alba root bark

Popis výsledku v původním jazyce

Ethnopharmacological relevance: Morus alba L. is used in traditional Chinese medicine for the treatment of various diseases, including bacterial infections and inflammation. As a rich source of phenolic compounds, the plant is an object of many phytochemical and pharmacological studies. Aim of the study: The aim of the study was to isolate and evaluate possible parallel antiviral, antibacterial, and anti-inflammatory activities of phenolic mulberry compounds. Materials and methods: Extensive chromatographic separation of mulberry root bark extract and in vitro biological screening of 26 constituents identified promising candidates for further pharmacological research. Selected compounds were screened for anti-infective and anti-inflammatory activities. Antiviral activity was determined by the plaque number reduction assay and by the titer reduction assay, antibacterial using broth microdilution method, and anti-inflammatory activity using COX Colorimetric inhibitor screening assay kit. One comp

Název v anglickém jazyce

Multiple In vitro biological effects of phenolic compounds from Morus alba root bark

Popis výsledku anglicky

Ethnopharmacological relevance: Morus alba L. is used in traditional Chinese medicine for the treatment of various diseases, including bacterial infections and inflammation. As a rich source of phenolic compounds, the plant is an object of many phytochemical and pharmacological studies. Aim of the study: The aim of the study was to isolate and evaluate possible parallel antiviral, antibacterial, and anti-inflammatory activities of phenolic mulberry compounds. Materials and methods: Extensive chromatographic separation of mulberry root bark extract and in vitro biological screening of 26 constituents identified promising candidates for further pharmacological research. Selected compounds were screened for anti-infective and anti-inflammatory activities. Antiviral activity was determined by the plaque number reduction assay and by the titer reduction assay, antibacterial using broth microdilution method, and anti-inflammatory activity using COX Colorimetric inhibitor screening assay kit. One comp

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10611 - Plant sciences, botany

Projekt

<a href="/cs/project/GA16-07193S" target="_blank" >GA16-07193S: Protizánětlivá aktivita vybraných stilbenů, 2-arylbenzofuranů a jejich metabolitů</a><br>

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal Of Ethnopharmacology

ISSN

0378-8741

e-ISSN

1872-7573

Svazek periodika

248

Číslo periodika v rámci svazku

112296

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

12

Strana od-do

1-12

Kód UT WoS článku

000503312800025

EID výsledku v databázi Scopus

2-s2.0-85074296613