Coke-derived graphene quantum dots as fluorescence nanoquencher in DNA detection

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F17%3A43913384" target="_blank" >RIV/60461373:22310/17:43913384 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.sciencedirect.com/science/article/pii/S2352940716302360" target="_blank" >http://www.sciencedirect.com/science/article/pii/S2352940716302360</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.apmt.2017.01.002" target="_blank" >10.1016/j.apmt.2017.01.002</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Coke-derived graphene quantum dots as fluorescence nanoquencher in DNA detection

Popis výsledku v původním jazyce

The recent emergence of coal and related fossil fuel products as an abundant and affordable source of graphene quantum dots (GQDs) highlights the potential of the carbon precursor in the development of simple and cost-effective DNA nanobiosensors. A coke-derived precursor- calcined petroleum coke- was utilized for the facile one-step synthesis of GQDs. Thereafter, DNA detection based on the coke-derived GQD platform exploited the differences in propensity towards spontaneous self-assembly with labelled single-stranded, and double-stranded DNA sequences. For this purpose, GQDs functioned as fluorescence resonance energy transfer (FRET) acceptors for DNA detection down to 0.004 nM. The sensing assay displays sensitivity over 3 orders of magnitudes. These results pave the way towards the identification of alternative nanomaterials for the development of inexpensive nanobiosensors for highly efficient, sensitive and selective detection of DNA.

Název v anglickém jazyce

Coke-derived graphene quantum dots as fluorescence nanoquencher in DNA detection

Popis výsledku anglicky

The recent emergence of coal and related fossil fuel products as an abundant and affordable source of graphene quantum dots (GQDs) highlights the potential of the carbon precursor in the development of simple and cost-effective DNA nanobiosensors. A coke-derived precursor- calcined petroleum coke- was utilized for the facile one-step synthesis of GQDs. Thereafter, DNA detection based on the coke-derived GQD platform exploited the differences in propensity towards spontaneous self-assembly with labelled single-stranded, and double-stranded DNA sequences. For this purpose, GQDs functioned as fluorescence resonance energy transfer (FRET) acceptors for DNA detection down to 0.004 nM. The sensing assay displays sensitivity over 3 orders of magnitudes. These results pave the way towards the identification of alternative nanomaterials for the development of inexpensive nanobiosensors for highly efficient, sensitive and selective detection of DNA.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10402 - Inorganic and nuclear chemistry

Projekt

<a href="/cs/project/GA15-09001S" target="_blank" >GA15-09001S: Chemické modifikace materiálů na bázi grafenu: Syntéza grafanu a halogengrafenu</a><br>

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Applied Materials Today

ISSN

2352-9407

e-ISSN

—

Svazek periodika

7

Číslo periodika v rámci svazku

JUN 2017

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

6

Strana od-do

138-143

Kód UT WoS článku

000405594100014

EID výsledku v databázi Scopus

2-s2.0-85014813819