Advanced Design of Microfluidic Chip Based on SPP-LSP Plasmonic Coupling for SERS Detection with High Sensitivity and Reliability

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F19%3A43918597" target="_blank" >RIV/60461373:22310/19:43918597 - isvavai.cz</a>

Výsledek na webu

<a href="https://pubs.acs.org/doi/10.1021/acs.jpcc.9b06751" target="_blank" >https://pubs.acs.org/doi/10.1021/acs.jpcc.9b06751</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1021/acs.jpcc.9b06751" target="_blank" >10.1021/acs.jpcc.9b06751</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Advanced Design of Microfluidic Chip Based on SPP-LSP Plasmonic Coupling for SERS Detection with High Sensitivity and Reliability

Popis výsledku v původním jazyce

In this work, we propose the preparation and investigation of advanced microfluidic surface-enhanced Raman spectroscopy (SERS) chip with a design. allowing high SERS enhancement and analysis reproducibility. The proposed chip implements the creation of periodical metal structure (grating) inside the microfluidic chip and further immobilization of gold multibranched nanoparticles (AuMs) with shaped edges on the grating surface. Such an approach allows achieving plasmonic coupling between the surface plasmon polariton wave, excited on the Au grating, and localized surface plasmon, excited on sharped edges of AuMs. As a result, a high enhancement of electric field in the space between AuMs was achieved, which results in the high SERS enhancement factor, confirmed by both, theoretical calculation and experimental measurements with a typical SERS analyte-R6G. In particular, it is possible to detect a vanishingly small concentration of R6G using the proposed plasmonic coupling, which sensitivity significantly exceeds previously reported limits in the case of microfluidic SERS measurements. We also observed the dependency of SERS intensity on the microfluidic flow rate and demonstrated the perfect reliability of the SERS signal, measured in the microfluidic regimes under constant flow rate.

Název v anglickém jazyce

Advanced Design of Microfluidic Chip Based on SPP-LSP Plasmonic Coupling for SERS Detection with High Sensitivity and Reliability

Popis výsledku anglicky

In this work, we propose the preparation and investigation of advanced microfluidic surface-enhanced Raman spectroscopy (SERS) chip with a design. allowing high SERS enhancement and analysis reproducibility. The proposed chip implements the creation of periodical metal structure (grating) inside the microfluidic chip and further immobilization of gold multibranched nanoparticles (AuMs) with shaped edges on the grating surface. Such an approach allows achieving plasmonic coupling between the surface plasmon polariton wave, excited on the Au grating, and localized surface plasmon, excited on sharped edges of AuMs. As a result, a high enhancement of electric field in the space between AuMs was achieved, which results in the high SERS enhancement factor, confirmed by both, theoretical calculation and experimental measurements with a typical SERS analyte-R6G. In particular, it is possible to detect a vanishingly small concentration of R6G using the proposed plasmonic coupling, which sensitivity significantly exceeds previously reported limits in the case of microfluidic SERS measurements. We also observed the dependency of SERS intensity on the microfluidic flow rate and demonstrated the perfect reliability of the SERS signal, measured in the microfluidic regimes under constant flow rate.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20501 - Materials engineering

Projekt

<a href="/cs/project/GA18-26170S" target="_blank" >GA18-26170S: Světlem laditelné konjugované polymery pro vratné spínání vodivosti</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Physical Chemistry C

ISSN

1932-7447

e-ISSN

—

Svazek periodika

123

Číslo periodika v rámci svazku

50

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

7

Strana od-do

30492-30498

Kód UT WoS článku

000503919500049

EID výsledku v databázi Scopus

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