Ligand-free Ullmann-type arylation of oxazolidinones by diaryliodonium salts

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F23%3A43934046" target="_blank" >RIV/60461373:22310/23:43934046 - isvavai.cz</a>

Výsledek na webu

<a href="http://DOI" target="_blank" >http://DOI</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1039/d2ob02122f" target="_blank" >10.1039/d2ob02122f</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Ligand-free Ullmann-type arylation of oxazolidinones by diaryliodonium salts

Popis výsledku v původním jazyce

The arylation of azaheterocycles can be considered as one of the most important processes for the preparation of various biologically active compounds. In the present work, we describe a method for the copper-catalyzed N-arylation of hindered oxazolidinones using diaryliodonium salts. The method succeeds in good to excellent yields for the arylation of 4-alkyloxazolidinones, including sterically hindered isopropyl- and tert-butyl-substituted. The efficiency of the method was demonstrated for a wide range of diaryliodonium salts - symmetric and unsymmetric as well as ortho-substituted derivatives. The developed approach will provide an important contribution in the development and preparation of novel drugs and bioactive molecules containing oxazolidinone moieties. © 2023 The Royal Society of Chemistry.

Název v anglickém jazyce

Ligand-free Ullmann-type arylation of oxazolidinones by diaryliodonium salts

Popis výsledku anglicky

The arylation of azaheterocycles can be considered as one of the most important processes for the preparation of various biologically active compounds. In the present work, we describe a method for the copper-catalyzed N-arylation of hindered oxazolidinones using diaryliodonium salts. The method succeeds in good to excellent yields for the arylation of 4-alkyloxazolidinones, including sterically hindered isopropyl- and tert-butyl-substituted. The efficiency of the method was demonstrated for a wide range of diaryliodonium salts - symmetric and unsymmetric as well as ortho-substituted derivatives. The developed approach will provide an important contribution in the development and preparation of novel drugs and bioactive molecules containing oxazolidinone moieties. © 2023 The Royal Society of Chemistry.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10401 - Organic chemistry

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

ORGANIC &amp; BIOMOLECULAR CHEMISTRY

ISSN

1477-0520

e-ISSN

—

Svazek periodika

21

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

6

Strana od-do

1952-1957

Kód UT WoS článku

000931652900001

EID výsledku v databázi Scopus

2-s2.0-85148677194