Homochiral Optical Fibers Coated with Nanoscale Films of Metal-Organic Frameworks and Double-Plasmonic Ag and Au for In Situ Enantioselective Detection

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F24%3A43929310" target="_blank" >RIV/60461373:22310/24:43929310 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/44555601:13440/24:43898408

Výsledek na webu

<a href="https://pubs.acs.org/doi/10.1021/acsanm.4c00624" target="_blank" >https://pubs.acs.org/doi/10.1021/acsanm.4c00624</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1021/acsanm.4c00624" target="_blank" >10.1021/acsanm.4c00624</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Homochiral Optical Fibers Coated with Nanoscale Films of Metal-Organic Frameworks and Double-Plasmonic Ag and Au for In Situ Enantioselective Detection

Popis výsledku v původním jazyce

Chiral recognition and detection of organic compounds represent an important task in the pharmaceutical, biological, and chemical industries since the difference between organic isomers strictly determines their biological activity and medical impact. Common enantioselective analysis performed with sophisticated equipment requires specially trained staff and a longer period of time. In this work, we propose a functional plasmonic fiber for online enantioselective detection and recognition of small organic molecules-cysteine, tyrosine, and omeprazole. Two nanothick layers of plasmon-active metals (Au and Ag) were deposited on the core(s) of a single optical fiber, giving rise to two plasmon absorption bands, which are well evident in transmitted light. The metal surface(s) was grafted with homochiral metal-organic frameworks (HMOFs), with subnanometer chiral pores, which ensured the enantioselective capture of organic enantiomers from their solution. The capture of organic moieties by grafted HMOF(s) (l- or d-MOF-6) results in their preconcentration near the plasmon-active metals, i.e., in the space of plasmonic “evanescent plasmon wave” excitation. As a result of the local enantiomer capture and corresponding changes in the shrouding refractive index, the wavelength shift of the plasmon absorption band(s) position occurs (for one plasmon absorption band in the case of one enantiomer presence or for both plasmon absorption bands in the case of an enantiomer mixture). Such a design of functional double-plasmon-active optical fiber allows the qualitative and quantitative detection of the enantiomers of small organic molecules. The proposed enantioselective detection approach is simple, fast, and based on low-cost equipment. © 2024 The Authors. Published by American Chemical Society.

Název v anglickém jazyce

Homochiral Optical Fibers Coated with Nanoscale Films of Metal-Organic Frameworks and Double-Plasmonic Ag and Au for In Situ Enantioselective Detection

Popis výsledku anglicky

Chiral recognition and detection of organic compounds represent an important task in the pharmaceutical, biological, and chemical industries since the difference between organic isomers strictly determines their biological activity and medical impact. Common enantioselective analysis performed with sophisticated equipment requires specially trained staff and a longer period of time. In this work, we propose a functional plasmonic fiber for online enantioselective detection and recognition of small organic molecules-cysteine, tyrosine, and omeprazole. Two nanothick layers of plasmon-active metals (Au and Ag) were deposited on the core(s) of a single optical fiber, giving rise to two plasmon absorption bands, which are well evident in transmitted light. The metal surface(s) was grafted with homochiral metal-organic frameworks (HMOFs), with subnanometer chiral pores, which ensured the enantioselective capture of organic enantiomers from their solution. The capture of organic moieties by grafted HMOF(s) (l- or d-MOF-6) results in their preconcentration near the plasmon-active metals, i.e., in the space of plasmonic “evanescent plasmon wave” excitation. As a result of the local enantiomer capture and corresponding changes in the shrouding refractive index, the wavelength shift of the plasmon absorption band(s) position occurs (for one plasmon absorption band in the case of one enantiomer presence or for both plasmon absorption bands in the case of an enantiomer mixture). Such a design of functional double-plasmon-active optical fiber allows the qualitative and quantitative detection of the enantiomers of small organic molecules. The proposed enantioselective detection approach is simple, fast, and based on low-cost equipment. © 2024 The Authors. Published by American Chemical Society.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20501 - Materials engineering

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

ACS Applied Nano Materials

ISSN

2574-0970

e-ISSN

—

Svazek periodika

7

Číslo periodika v rámci svazku

8

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

8

Strana od-do

9210-9217

Kód UT WoS článku

001203570600001

EID výsledku v databázi Scopus

2-s2.0-85190726951