Stanovení polybromovaných difenyletherů ve vzorcích mateřského mléka v České republice. Studie porovnávající hmotnostní spektrometrii s negativní chemickou ionizací a time of flight vysokorozlišovací hmotnostní spektrometrii

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F04%3A00013083" target="_blank" >RIV/60461373:22330/04:00013083 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Determination of polybrominated diphenyl ethers in human milk samples in the Czech Republic. Comparative study of negative chemical ionisation mass spectrometry and time-of-flight high-resolution mass spectrometry

Popis výsledku v původním jazyce

In the Czech Republic no study on the levels of brominated flame retardants in human milk has been conducted, yet. In the first step analytical method for determination of PBDEs in this bioindicator matrix was implemented. Liquid-liquid extraction (LLE)(hexane, diethyl ether), followed by gel permeation chromatography was employed for isolation of PBDEs. Identification and quantification of PBDEs was carried out by GC-MS operated in negative chemical ionisation (NCI). Two mass spectrometric technologies, one employing quadrupole and the other one high resolution (HR) time-of-flight (TOF) analyzer, etc. were used in our study. Detection limits (LODs) obtained by quadrupole analyzer ranged from 0.02 to 0.05 ng g-1 lipid weight, using high resolution time-of-flight analyzer LODs were significantly lower, ranging from 0.002-0.005 ng g-1 lipid weight, what enabled detection of minor PBDE congeners. Within this pilot study 103 breast milk samples, obtained from mothers living in Olomouc reg

Název v anglickém jazyce

Determination of polybrominated diphenyl ethers in human milk samples in the Czech Republic. Comparative study of negative chemical ionisation mass spectrometry and time-of-flight high-resolution mass spectrometry

Popis výsledku anglicky

In the Czech Republic no study on the levels of brominated flame retardants in human milk has been conducted, yet. In the first step analytical method for determination of PBDEs in this bioindicator matrix was implemented. Liquid-liquid extraction (LLE)(hexane, diethyl ether), followed by gel permeation chromatography was employed for isolation of PBDEs. Identification and quantification of PBDEs was carried out by GC-MS operated in negative chemical ionisation (NCI). Two mass spectrometric technologies, one employing quadrupole and the other one high resolution (HR) time-of-flight (TOF) analyzer, etc. were used in our study. Detection limits (LODs) obtained by quadrupole analyzer ranged from 0.02 to 0.05 ng g-1 lipid weight, using high resolution time-of-flight analyzer LODs were significantly lower, ranging from 0.002-0.005 ng g-1 lipid weight, what enabled detection of minor PBDE congeners. Within this pilot study 103 breast milk samples, obtained from mothers living in Olomouc reg

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2004

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Anal.Chim.Acta

ISSN

0003-2670

e-ISSN

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Svazek periodika

520

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

7

Strana od-do

237-243

Kód UT WoS článku

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EID výsledku v databázi Scopus

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