The determination of perfluoroalkyl substances, brominated flame retardants and their metabolites in human breast milk and infant formula
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F13%3A43896642" target="_blank" >RIV/60461373:22330/13:43896642 - isvavai.cz</a>
Výsledek na webu
<a href="http://ac.els-cdn.com/S003991401300698X/1-s2.0-S003991401300698X-main.pdf?_tid=52269a38-9af3-11e3-b8c5-00000aab0f6b&acdnat=1392985739_aa77dabd91eb67b4393bda48af3dcdf8" target="_blank" >http://ac.els-cdn.com/S003991401300698X/1-s2.0-S003991401300698X-main.pdf?_tid=52269a38-9af3-11e3-b8c5-00000aab0f6b&acdnat=1392985739_aa77dabd91eb67b4393bda48af3dcdf8</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.talanta.2013.08.040" target="_blank" >10.1016/j.talanta.2013.08.040</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
The determination of perfluoroalkyl substances, brominated flame retardants and their metabolites in human breast milk and infant formula
Popis výsledku v původním jazyce
In the present study, a novel analytical approach for the simultaneous determination of 18 perfluoroalkyl substances (PFASs) and 11 brominated flame retardants (BFRs) including their hydroxylated metabolites and brominated phenols has been developed andvalidated for breast milk and infant formula. The sample preparation procedure based on extraction using acetonitrile and subsequent purification by dispersive solid-phase extraction (d-SPE) employing C18 sorbent is rapid, simple and high-throughput. Ultra-high performance liquid chromatography (UHPLC) interfaced with a tandem mass spectrometry (MS/MS) was employed for the identification/quantification of these compounds. The method recoveries of target compounds for both matrices ranged from 80% to 117% with relative standard deviations lower than 28% and quantification limits in the range of 3?200 pg/mL for milk and 5?450 pg/g for infant formula. Within the pilot study, the new method was used for the analysis of PFASs and BFRs in 50
Název v anglickém jazyce
The determination of perfluoroalkyl substances, brominated flame retardants and their metabolites in human breast milk and infant formula
Popis výsledku anglicky
In the present study, a novel analytical approach for the simultaneous determination of 18 perfluoroalkyl substances (PFASs) and 11 brominated flame retardants (BFRs) including their hydroxylated metabolites and brominated phenols has been developed andvalidated for breast milk and infant formula. The sample preparation procedure based on extraction using acetonitrile and subsequent purification by dispersive solid-phase extraction (d-SPE) employing C18 sorbent is rapid, simple and high-throughput. Ultra-high performance liquid chromatography (UHPLC) interfaced with a tandem mass spectrometry (MS/MS) was employed for the identification/quantification of these compounds. The method recoveries of target compounds for both matrices ranged from 80% to 117% with relative standard deviations lower than 28% and quantification limits in the range of 3?200 pg/mL for milk and 5?450 pg/g for infant formula. Within the pilot study, the new method was used for the analysis of PFASs and BFRs in 50
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
GM - Potravinářství
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/7E08068" target="_blank" >7E08068: CONtaminants in Food and Feed: Inexpensive DEtectioN for Control of Exposure</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Ostatní
Rok uplatnění
2013
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Talanta
ISSN
0039-9140
e-ISSN
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Svazek periodika
117
Číslo periodika v rámci svazku
1
Stát vydavatele periodika
NL - Nizozemsko
Počet stran výsledku
8
Strana od-do
318-325
Kód UT WoS článku
000328801400047
EID výsledku v databázi Scopus
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