The determination of perfluoroalkyl substances, brominated flame retardants and their metabolites in human breast milk and infant formula

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F13%3A43896642" target="_blank" >RIV/60461373:22330/13:43896642 - isvavai.cz</a>

Výsledek na webu

<a href="http://ac.els-cdn.com/S003991401300698X/1-s2.0-S003991401300698X-main.pdf?_tid=52269a38-9af3-11e3-b8c5-00000aab0f6b&acdnat=1392985739_aa77dabd91eb67b4393bda48af3dcdf8" target="_blank" >http://ac.els-cdn.com/S003991401300698X/1-s2.0-S003991401300698X-main.pdf?_tid=52269a38-9af3-11e3-b8c5-00000aab0f6b&acdnat=1392985739_aa77dabd91eb67b4393bda48af3dcdf8</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.talanta.2013.08.040" target="_blank" >10.1016/j.talanta.2013.08.040</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The determination of perfluoroalkyl substances, brominated flame retardants and their metabolites in human breast milk and infant formula

Popis výsledku v původním jazyce

In the present study, a novel analytical approach for the simultaneous determination of 18 perfluoroalkyl substances (PFASs) and 11 brominated flame retardants (BFRs) including their hydroxylated metabolites and brominated phenols has been developed andvalidated for breast milk and infant formula. The sample preparation procedure based on extraction using acetonitrile and subsequent purification by dispersive solid-phase extraction (d-SPE) employing C18 sorbent is rapid, simple and high-throughput. Ultra-high performance liquid chromatography (UHPLC) interfaced with a tandem mass spectrometry (MS/MS) was employed for the identification/quantification of these compounds. The method recoveries of target compounds for both matrices ranged from 80% to 117% with relative standard deviations lower than 28% and quantification limits in the range of 3?200 pg/mL for milk and 5?450 pg/g for infant formula. Within the pilot study, the new method was used for the analysis of PFASs and BFRs in 50

Název v anglickém jazyce

The determination of perfluoroalkyl substances, brominated flame retardants and their metabolites in human breast milk and infant formula

Popis výsledku anglicky

In the present study, a novel analytical approach for the simultaneous determination of 18 perfluoroalkyl substances (PFASs) and 11 brominated flame retardants (BFRs) including their hydroxylated metabolites and brominated phenols has been developed andvalidated for breast milk and infant formula. The sample preparation procedure based on extraction using acetonitrile and subsequent purification by dispersive solid-phase extraction (d-SPE) employing C18 sorbent is rapid, simple and high-throughput. Ultra-high performance liquid chromatography (UHPLC) interfaced with a tandem mass spectrometry (MS/MS) was employed for the identification/quantification of these compounds. The method recoveries of target compounds for both matrices ranged from 80% to 117% with relative standard deviations lower than 28% and quantification limits in the range of 3?200 pg/mL for milk and 5?450 pg/g for infant formula. Within the pilot study, the new method was used for the analysis of PFASs and BFRs in 50

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GM - Potravinářství

OECD FORD obor

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Projekt

<a href="/cs/project/7E08068" target="_blank" >7E08068: CONtaminants in Food and Feed: Inexpensive DEtectioN for Control of Exposure</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Talanta

ISSN

0039-9140

e-ISSN

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Svazek periodika

117

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

8

Strana od-do

318-325

Kód UT WoS článku

000328801400047

EID výsledku v databázi Scopus

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