Preparation of amorphous antimicrobial selenium nanoparticles stabilized by odor suppressing surfactant polysorbate 20

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F15%3A43899719" target="_blank" >RIV/60461373:22330/15:43899719 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60461373:22310/15:43899719

Výsledek na webu

<a href="http://www.sciencedirect.com/science/article/pii/S0167577X15004760" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0167577X15004760</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.matlet.2015.03.092" target="_blank" >10.1016/j.matlet.2015.03.092</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Preparation of amorphous antimicrobial selenium nanoparticles stabilized by odor suppressing surfactant polysorbate 20

Popis výsledku v původním jazyce

Selenium nanoparticles (SeNPs) have recently drawn big attention not only as possible anticancer agents, but also as novel antimicrobials. Nevertheless, there are still strong limitations in particle preparation and their stabilization. Here, we report on synthesis of SeNPs of various sizes by a facile reduction method. Ascorbic acid was used as a reduction agent and a common emulsifier polysorbate 20 as a surfactant and to control the reaction kinetics. We characterized the quality and the size of theprepared nanoparticles by TEM and Zetasizer, respectively. The presence of selenium was assessed by AAS analysis, the amorphous structure of SeNPs by XRD measurements. Antimicrobial potential of these novel polysorbate 20 stabilized SeNPs was tested in vitro using three bacterial strains. Even at a very low concentration of selenium, SeNPs showed potent antibacterial activity against common biofilm-forming Gram-positive bacteria Staphylococcus aureus and Staphylococcus epidermidis. This

Název v anglickém jazyce

Preparation of amorphous antimicrobial selenium nanoparticles stabilized by odor suppressing surfactant polysorbate 20

Popis výsledku anglicky

Selenium nanoparticles (SeNPs) have recently drawn big attention not only as possible anticancer agents, but also as novel antimicrobials. Nevertheless, there are still strong limitations in particle preparation and their stabilization. Here, we report on synthesis of SeNPs of various sizes by a facile reduction method. Ascorbic acid was used as a reduction agent and a common emulsifier polysorbate 20 as a surfactant and to control the reaction kinetics. We characterized the quality and the size of theprepared nanoparticles by TEM and Zetasizer, respectively. The presence of selenium was assessed by AAS analysis, the amorphous structure of SeNPs by XRD measurements. Antimicrobial potential of these novel polysorbate 20 stabilized SeNPs was tested in vitro using three bacterial strains. Even at a very low concentration of selenium, SeNPs showed potent antibacterial activity against common biofilm-forming Gram-positive bacteria Staphylococcus aureus and Staphylococcus epidermidis. This

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CA - Anorganická chemie

OECD FORD obor

—

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Materials Letters

ISSN

0167-577X

e-ISSN

—

Svazek periodika

152

Číslo periodika v rámci svazku

August

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

3

Strana od-do

207-209

Kód UT WoS článku

000356188100056

EID výsledku v databázi Scopus

—