Investigation of Secondary Metabolites and Their Bioactive Potential in Various Iris Species and Cultivars Grown under Different Cultivation Conditions

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F25%3A43932469" target="_blank" >RIV/60461373:22330/25:43932469 - isvavai.cz</a>

Výsledek na webu

<a href="https://pubs.acs.org/doi/10.1021/acsomega.5c06354" target="_blank" >https://pubs.acs.org/doi/10.1021/acsomega.5c06354</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1021/acsomega.5c06354" target="_blank" >10.1021/acsomega.5c06354</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Investigation of Secondary Metabolites and Their Bioactive Potential in Various Iris Species and Cultivars Grown under Different Cultivation Conditions

Popis výsledku v původním jazyce

This study analyzed the bioactive secondary metabolites in leaves and roots with rhizomes of various Iris species and cultivars (subgenus Iris and Limniris) grown under different conditions. Plants were cultivated in aeroponics and hydroponics and treated with a feather hydrolysate as an alternative nutrient source or arbuscular mycorrhizal fungi (AMF) to promote metabolite production. Phytochemical profiling was performed by using UHPLC-HRMS/MS, aided by in silico fragmentation for compound identification. Chemometric analyses revealed differences in the metabolic profiles between plant parts, including upregulation of phenolic acids, steroids, and C-glycosyl xanthones in the leaves and of stilbenes, triterpenoids, and benzophenones in the roots with rhizomes. Variations between the subgenera Iris and Limniris revealed possible chemotaxonomic markers, while cultivars of the same species showed a close similarity. Hydroponics resulted in upregulation of 232 metabolites, including flavone and isoflavonoid glycosides, compared to 42 upregulated metabolites in aeroponics, like xanthones and benzofurans. Neither feather hydrolysate nor AMF significantly altered the profile of detected metabolites. The correlation of the phytochemical profiles with biochemical assays of the Iris extracts indicated metabolites with cytotoxic, antimicrobial, and anti-inflammatory potential, including both known bioactive compounds (e.g., iridin, phalerin, or p-coumaric acid) and compounds with no published bioactivity data (e.g., irisjaponin A).

Název v anglickém jazyce

Investigation of Secondary Metabolites and Their Bioactive Potential in Various Iris Species and Cultivars Grown under Different Cultivation Conditions

Popis výsledku anglicky

This study analyzed the bioactive secondary metabolites in leaves and roots with rhizomes of various Iris species and cultivars (subgenus Iris and Limniris) grown under different conditions. Plants were cultivated in aeroponics and hydroponics and treated with a feather hydrolysate as an alternative nutrient source or arbuscular mycorrhizal fungi (AMF) to promote metabolite production. Phytochemical profiling was performed by using UHPLC-HRMS/MS, aided by in silico fragmentation for compound identification. Chemometric analyses revealed differences in the metabolic profiles between plant parts, including upregulation of phenolic acids, steroids, and C-glycosyl xanthones in the leaves and of stilbenes, triterpenoids, and benzophenones in the roots with rhizomes. Variations between the subgenera Iris and Limniris revealed possible chemotaxonomic markers, while cultivars of the same species showed a close similarity. Hydroponics resulted in upregulation of 232 metabolites, including flavone and isoflavonoid glycosides, compared to 42 upregulated metabolites in aeroponics, like xanthones and benzofurans. Neither feather hydrolysate nor AMF significantly altered the profile of detected metabolites. The correlation of the phytochemical profiles with biochemical assays of the Iris extracts indicated metabolites with cytotoxic, antimicrobial, and anti-inflammatory potential, including both known bioactive compounds (e.g., iridin, phalerin, or p-coumaric acid) and compounds with no published bioactivity data (e.g., irisjaponin A).

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10400 - Chemical sciences

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

ACS Omega

ISSN

2470-1343

e-ISSN

—

Svazek periodika

10

Číslo periodika v rámci svazku

43

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

16

Strana od-do

51256-51271

Kód UT WoS článku

001596590600001

EID výsledku v databázi Scopus

2-s2.0-105024133150