"Green chemistry" příprava oligopyrrolových makrocyklových prekursorů: Nová metodika pro syntézu dipyrromethanů a tripyrromethanů ve vodě

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F04%3A00011126" target="_blank" >RIV/60461373:22340/04:00011126 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60461373:22340/04:00013194

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Green chemistry for preparation of oligopyrrole macrocycles precursors: Novel methodology for dipyrromethanes and tripyrromethanes synthesis in water

Popis výsledku v původním jazyce

A novel methodology for preparation of linear oligopyrroles is presented. Synthetic protocol uses water as a solvent for acid catalysed condensation of an aldehyde or ketone with unsubstituted pyrrole. While the most procedures for the above-mentioned compounds are performed in organic solvents, or large excess of pyrrole (used as solvent), we present here a novel, mild and efficient procedure for selective preparation of linear oligopyrroles in aqueous environment. Preparation of dipyrromethanes 3 andtripyrromethanes 4 was optimised by varying the molar ratio and concentrations of starting compounds (aldehyde to pyrrole) and acid catalyst. The high initial concentration of aldehyde and pyrrole leads to the preferential formation of 3, where the driving force for the product formation is precipitation of 3 from water solution; the reaction proceeds at room temperature within a couple of minutes in excellent yields. On the other hand, low concentration of starting compounds led to pref

Název v anglickém jazyce

Green chemistry for preparation of oligopyrrole macrocycles precursors: Novel methodology for dipyrromethanes and tripyrromethanes synthesis in water

Popis výsledku anglicky

A novel methodology for preparation of linear oligopyrroles is presented. Synthetic protocol uses water as a solvent for acid catalysed condensation of an aldehyde or ketone with unsubstituted pyrrole. While the most procedures for the above-mentioned compounds are performed in organic solvents, or large excess of pyrrole (used as solvent), we present here a novel, mild and efficient procedure for selective preparation of linear oligopyrroles in aqueous environment. Preparation of dipyrromethanes 3 andtripyrromethanes 4 was optimised by varying the molar ratio and concentrations of starting compounds (aldehyde to pyrrole) and acid catalyst. The high initial concentration of aldehyde and pyrrole leads to the preferential formation of 3, where the driving force for the product formation is precipitation of 3 from water solution; the reaction proceeds at room temperature within a couple of minutes in excellent yields. On the other hand, low concentration of starting compounds led to pref

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

<a href="/cs/project/GA203%2F02%2F0420" target="_blank" >GA203/02/0420: Tetrapyrrolové metalokomplexy: Modifikace triplexových struktur nukleových kyselin</a><br>

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2004

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Collection of Czechoslovak Chemical Communications

ISSN

0010-0765

e-ISSN

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Svazek periodika

69

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

11

Strana od-do

1126-1136

Kód UT WoS článku

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EID výsledku v databázi Scopus

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