Influence of polyaniline on the potentiometric determination of risedronate with ion-selective membranes

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F10%3A00023389" target="_blank" >RIV/60461373:22340/10:00023389 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Influence of polyaniline on the potentiometric determination of risedronate with ion-selective membranes

Popis výsledku v původním jazyce

A novel kind of potentiometric sensor for the determination of risedronate in pharmaceutical products is proposed. This potentiometric sensor is comprised of a poly(vinyl chloride) (PVC) membrane based on an anion-exchanger, tridodecylmethylammonium chloride (TDDMACl), and coated with a polyaniline (PANI) layer. The potentiometric response towards a highly hydrated risedronate species was strongly promoted by the presence of the PANI layer. In contrast to uncoated membranes, the PANI-coated membrane exhibited a sensitivity of ?39.9 ? 0.9 mV decade?1 and the detection limit reached 0.45 mg mL?1. The results of the potentiometric analysis of risedronate agreed with those obtained with a validated chromatographic method. The TDDMACl-based membrane coatedwith the PANI layer differentiated 0.94 wt % and 3.44 wt % of a specific contaminant in 1.6 mg mL?1 risedronate.

Název v anglickém jazyce

Influence of polyaniline on the potentiometric determination of risedronate with ion-selective membranes

Popis výsledku anglicky

A novel kind of potentiometric sensor for the determination of risedronate in pharmaceutical products is proposed. This potentiometric sensor is comprised of a poly(vinyl chloride) (PVC) membrane based on an anion-exchanger, tridodecylmethylammonium chloride (TDDMACl), and coated with a polyaniline (PANI) layer. The potentiometric response towards a highly hydrated risedronate species was strongly promoted by the presence of the PANI layer. In contrast to uncoated membranes, the PANI-coated membrane exhibited a sensitivity of ?39.9 ? 0.9 mV decade?1 and the detection limit reached 0.45 mg mL?1. The results of the potentiometric analysis of risedronate agreed with those obtained with a validated chromatographic method. The TDDMACl-based membrane coatedwith the PANI layer differentiated 0.94 wt % and 3.44 wt % of a specific contaminant in 1.6 mg mL?1 risedronate.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2010

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Analytical Methods

ISSN

1759-9660

e-ISSN

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Svazek periodika

2

Číslo periodika v rámci svazku

10

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

4

Strana od-do

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Kód UT WoS článku

000283959600029

EID výsledku v databázi Scopus

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