Adaptive Control of Saccharomyces cerevisiae Yeasts Fed-Batch Cultivations

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F13%3A43895134" target="_blank" >RIV/60461373:22340/13:43895134 - isvavai.cz</a>

Výsledek na webu

<a href="http://pierre.fkit.hr/hdki/cabeq/pdf/27_3_2013/Pages%20from%20Cabeq%202013-03-07%20ver%2002.pdf" target="_blank" >http://pierre.fkit.hr/hdki/cabeq/pdf/27_3_2013/Pages%20from%20Cabeq%202013-03-07%20ver%2002.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Adaptive Control of Saccharomyces cerevisiae Yeasts Fed-Batch Cultivations

Popis výsledku v původním jazyce

In this paper, the application of an adaptive algorithm for control of fed-batch bioprocess capable of coping with time-variant process properties in the presence of uncertainties is introduced. The proposed adaptive controller uses Maršík?s heuristic algorithm for adaptation based on control error oscillation rate criterion without the need of a mathematical model of the controlled process or any special test signals. The intended application of the resulting controller was off-gas CO2 concentration control in fed-batch yeast cultivations where the set point has the form of a time-varying concentration profile. The controller has been tested in a series of experimental fed-batch cultivations with D7 Saccharomyces cerevisiae strain, a UV mutant suitable for ergosterol production, in 7-litre laboratory bioreactor. Obtained results demonstrate good properties of this adaptive controller that can be used without the need for a tedious parameter identification of the complex bioprocess.

Název v anglickém jazyce

Adaptive Control of Saccharomyces cerevisiae Yeasts Fed-Batch Cultivations

Popis výsledku anglicky

In this paper, the application of an adaptive algorithm for control of fed-batch bioprocess capable of coping with time-variant process properties in the presence of uncertainties is introduced. The proposed adaptive controller uses Maršík?s heuristic algorithm for adaptation based on control error oscillation rate criterion without the need of a mathematical model of the controlled process or any special test signals. The intended application of the resulting controller was off-gas CO2 concentration control in fed-batch yeast cultivations where the set point has the form of a time-varying concentration profile. The controller has been tested in a series of experimental fed-batch cultivations with D7 Saccharomyces cerevisiae strain, a UV mutant suitable for ergosterol production, in 7-litre laboratory bioreactor. Obtained results demonstrate good properties of this adaptive controller that can be used without the need for a tedious parameter identification of the complex bioprocess.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

JD - Využití počítačů, robotika a její aplikace

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Chemical and Biochemical Engineering Quarterly

ISSN

0352-9568

e-ISSN

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Svazek periodika

27

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

HR - Chorvatská republika

Počet stran výsledku

10

Strana od-do

297-306

Kód UT WoS článku

000326058300007

EID výsledku v databázi Scopus

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