Nanoparticles functionalized with phenylboronic acid for the potentiometric detection of saccharides

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F16%3A43901556" target="_blank" >RIV/60461373:22340/16:43901556 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11310/16:10321853

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.jelechem.2015.12.009" target="_blank" >http://dx.doi.org/10.1016/j.jelechem.2015.12.009</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jelechem.2015.12.009" target="_blank" >10.1016/j.jelechem.2015.12.009</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Nanoparticles functionalized with phenylboronic acid for the potentiometric detection of saccharides

Popis výsledku v původním jazyce

We have proposed a concept for the analytical application of modified gold nanoparticles in potentiometric sensors. The main idea is to embed modified gold nanoparticles as receptor units during electropolymerization into a polymeric matrix which should serve as a transducer of the potentiometric signal. The concept was verified using a model system based on gold nanoparticles modified with mercaptophenylboronic acid (MPBA-AuNPs) as a receptor of saccharides in a pH-sensitive polymer matrix, namely polyaniline (PANI). The determination of saccharides, in particular D-glucose, is based on the determination of released protons as products of the reaction between mercaptophenylboronic acid and saccharides. Differential pulse voltammetry showed that approximately 33% of the MPBA-AuNPs present in the polymerization mixture were built into the PANI polymeric film. The absorption and reflectivity spectra confirmed the recognition process occurring between mercaptophenylboronic acid and D-glucose inside the pH-sensitive polymeric matrix. A potentiometric response of MPBA-AuNP-modified PANI electrodes towards D-glucose in the concentration range from 0.31 up to 33 mM with a sensitivity of +47 mV/decade was verified. The MPBA-AuNP-modified PANI film can be considered to be a saccharide-sensitive receptor layer exhibiting an indirect mechanism of signal generation.

Název v anglickém jazyce

Nanoparticles functionalized with phenylboronic acid for the potentiometric detection of saccharides

Popis výsledku anglicky

We have proposed a concept for the analytical application of modified gold nanoparticles in potentiometric sensors. The main idea is to embed modified gold nanoparticles as receptor units during electropolymerization into a polymeric matrix which should serve as a transducer of the potentiometric signal. The concept was verified using a model system based on gold nanoparticles modified with mercaptophenylboronic acid (MPBA-AuNPs) as a receptor of saccharides in a pH-sensitive polymer matrix, namely polyaniline (PANI). The determination of saccharides, in particular D-glucose, is based on the determination of released protons as products of the reaction between mercaptophenylboronic acid and saccharides. Differential pulse voltammetry showed that approximately 33% of the MPBA-AuNPs present in the polymerization mixture were built into the PANI polymeric film. The absorption and reflectivity spectra confirmed the recognition process occurring between mercaptophenylboronic acid and D-glucose inside the pH-sensitive polymeric matrix. A potentiometric response of MPBA-AuNP-modified PANI electrodes towards D-glucose in the concentration range from 0.31 up to 33 mM with a sensitivity of +47 mV/decade was verified. The MPBA-AuNP-modified PANI film can be considered to be a saccharide-sensitive receptor layer exhibiting an indirect mechanism of signal generation.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CG - Elektrochemie

OECD FORD obor

—

Projekt

<a href="/cs/project/GA15-02815S" target="_blank" >GA15-02815S: Nové rozpoznávací principy a přístupy k elektrochemické detekci nádorových markerů</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

JOURNAL OF ELECTROANALYTICAL CHEMISTRY

ISSN

1572-6657

e-ISSN

—

Svazek periodika

761

Číslo periodika v rámci svazku

neuvedeno

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

6

Strana od-do

106-111

Kód UT WoS článku

000369205400015

EID výsledku v databázi Scopus

2-s2.0-84952029788