Influence of channel height on mixing efficiency and synthesis of iron oxide nanoparticles using droplet-based microfluidics

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F20%3A43920681" target="_blank" >RIV/60461373:22340/20:43920681 - isvavai.cz</a>

Výsledek na webu

<a href="https://pubs.rsc.org/en/content/articlepdf/2020/ra/d0ra02470h" target="_blank" >https://pubs.rsc.org/en/content/articlepdf/2020/ra/d0ra02470h</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1039/d0ra02470h" target="_blank" >10.1039/d0ra02470h</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Influence of channel height on mixing efficiency and synthesis of iron oxide nanoparticles using droplet-based microfluidics

Popis výsledku v původním jazyce

Microfluidic devices, allowing superior control over the spatial and temporal distribution of chemical substances and high process reproducibility, are nowadays essential in various research areas and industrial fields where the traditional &quot;macroscopic&quot; approach was no longer able to keep up with the increasing demands of high-end applications. In the present work, internal mixing of droplets formed by a flow-focusing X-junction at constant flow rates of both phases for three different channel heights (i.e. 20, 40 and 60 μm) was investigated and characterised. Both experimental methods and 3D CFD simulations were employed in order to resolve governing factors having an impact on internal mixing and homogenization time of model tracers inside of droplet reactors. Additionally, the influence of channel height on internal mixing was experimentally studied for continuous preparation of iron oxide nanoparticles by co-precipitation reaction. Since the initial nucleation phase is strongly affected by mixing and spatial distribution of all reactants, the final particle size and particle size distribution (PSD) can be used as direct indicators of mixing performance. It has been demonstrated that the smallest 20 μm channels provided narrower PSD and smaller particle mean size compared to higher channels. This journal is © 2020 The Royal Society of Chemistry.

Název v anglickém jazyce

Influence of channel height on mixing efficiency and synthesis of iron oxide nanoparticles using droplet-based microfluidics

Popis výsledku anglicky

Microfluidic devices, allowing superior control over the spatial and temporal distribution of chemical substances and high process reproducibility, are nowadays essential in various research areas and industrial fields where the traditional &quot;macroscopic&quot; approach was no longer able to keep up with the increasing demands of high-end applications. In the present work, internal mixing of droplets formed by a flow-focusing X-junction at constant flow rates of both phases for three different channel heights (i.e. 20, 40 and 60 μm) was investigated and characterised. Both experimental methods and 3D CFD simulations were employed in order to resolve governing factors having an impact on internal mixing and homogenization time of model tracers inside of droplet reactors. Additionally, the influence of channel height on internal mixing was experimentally studied for continuous preparation of iron oxide nanoparticles by co-precipitation reaction. Since the initial nucleation phase is strongly affected by mixing and spatial distribution of all reactants, the final particle size and particle size distribution (PSD) can be used as direct indicators of mixing performance. It has been demonstrated that the smallest 20 μm channels provided narrower PSD and smaller particle mean size compared to higher channels. This journal is © 2020 The Royal Society of Chemistry.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20402 - Chemical process engineering

Projekt

<a href="/cs/project/GJ17-11851Y" target="_blank" >GJ17-11851Y: Syntéza biomimetických nanočásticových materiálů připravených mikrofluidní platformou a zkoumání jejich interakce s buňkami</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

RSC Advances

ISSN

2046-2069

e-ISSN

—

Svazek periodika

10

Číslo periodika v rámci svazku

26

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

11

Strana od-do

15179-15189

Kód UT WoS článku

000530037900020

EID výsledku v databázi Scopus

2-s2.0-85084112664