ABA-C15: A New Dye for Probing Solvent Relaxation in Phospholipid Bilayers.

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F02%3A54020186" target="_blank" >RIV/61388955:_____/02:54020186 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68407700:21340/02:04079391 RIV/00216275:25310/02:00000212

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

ABA-C15: A New Dye for Probing Solvent Relaxation in Phospholipid Bilayers.

Popis výsledku v původním jazyce

We synthesized and studied N-palmitoyl-3-aminobenzanthrone (ABA-C15), which we proved to be an advantageous new fluorescent phospholipid membrane label. While the absorption of ABA-C15 in protic solvents shows negative solvatochromism, its fluorescence emission is substantially red-shifted when the polarity of the solvent is increased. ABA-C15 is excitable by lasers emitting in the range between 390 and 490 nm; it exhibits reasonable quantum yields in protic solvents and binds with high affinity to small unilamellar phospholipid vesicles. Absorption, steady state fluorescence, and solvent relaxation data indicate that the aminobenzanthrone chromophore is located in the headgroup region of phospholipid bilayers in the liquid crystalline state of small unilamellar vesicles. The solvent relaxation kinetics probed by ABA-C15 in the liquid crystalline state is characterized by three solvent relaxation times in the order of 0.05, 0.2, and 1.5 ns, respectively.

Název v anglickém jazyce

ABA-C15: A New Dye for Probing Solvent Relaxation in Phospholipid Bilayers.

Popis výsledku anglicky

We synthesized and studied N-palmitoyl-3-aminobenzanthrone (ABA-C15), which we proved to be an advantageous new fluorescent phospholipid membrane label. While the absorption of ABA-C15 in protic solvents shows negative solvatochromism, its fluorescence emission is substantially red-shifted when the polarity of the solvent is increased. ABA-C15 is excitable by lasers emitting in the range between 390 and 490 nm; it exhibits reasonable quantum yields in protic solvents and binds with high affinity to small unilamellar phospholipid vesicles. Absorption, steady state fluorescence, and solvent relaxation data indicate that the aminobenzanthrone chromophore is located in the headgroup region of phospholipid bilayers in the liquid crystalline state of small unilamellar vesicles. The solvent relaxation kinetics probed by ABA-C15 in the liquid crystalline state is characterized by three solvent relaxation times in the order of 0.05, 0.2, and 1.5 ns, respectively.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CF - Fyzikální chemie a teoretická chemie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2002

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Langmuir

ISSN

0743-7463

e-ISSN

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Svazek periodika

18

Číslo periodika v rámci svazku

24

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

7

Strana od-do

9276-9282

Kód UT WoS článku

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EID výsledku v databázi Scopus

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