Quantification of Acetonitrile in Exhaled Breath and Urinary Headspace Using Selected Ion Flow Tube Mass Spectrometry.

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F03%3A54030123" target="_blank" >RIV/61388955:_____/03:54030123 - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Quantification of Acetonitrile in Exhaled Breath and Urinary Headspace Using Selected Ion Flow Tube Mass Spectrometry.

Popis výsledku v původním jazyce

A study has been carried out of acetonitrile in exhaled breath and in the headspace of urine from several cigarette smokers and several non-smokers using selected ion flow tube mass spectrometry, SIFT-MS. The ion chemistry involved in the detection of acetonitrile in the gas phase by SIFT-MS using H3O+ ions is outlined. Further to this, experiments have been carried out to determine the Henry's Law partition coefficients for dilute aqueous solutions of acetonitrile, which allow the determination of liquid phase urinary acetonitrile concentrations from headspace concentrations. The results of this study show that acetonitrile is readily detected by SIFT-MS in the breath and urinary headspace of smokers at levels dependent on the cigarette consumption, but is practically absent from the breath and urine headspace of non-smokers. Exploiting the measured values of the Henry's Law partition coefficients, the urinary phase concentrations have been deduced.

Název v anglickém jazyce

Quantification of Acetonitrile in Exhaled Breath and Urinary Headspace Using Selected Ion Flow Tube Mass Spectrometry.

Popis výsledku anglicky

A study has been carried out of acetonitrile in exhaled breath and in the headspace of urine from several cigarette smokers and several non-smokers using selected ion flow tube mass spectrometry, SIFT-MS. The ion chemistry involved in the detection of acetonitrile in the gas phase by SIFT-MS using H3O+ ions is outlined. Further to this, experiments have been carried out to determine the Henry's Law partition coefficients for dilute aqueous solutions of acetonitrile, which allow the determination of liquid phase urinary acetonitrile concentrations from headspace concentrations. The results of this study show that acetonitrile is readily detected by SIFT-MS in the breath and urinary headspace of smokers at levels dependent on the cigarette consumption, but is practically absent from the breath and urine headspace of non-smokers. Exploiting the measured values of the Henry's Law partition coefficients, the urinary phase concentrations have been deduced.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CF - Fyzikální chemie a teoretická chemie

OECD FORD obor

—

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2003

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Mass Spectrometry

ISSN

1387-3806

e-ISSN

—

Svazek periodika

228

Číslo periodika v rámci svazku

N/A

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

11

Strana od-do

655-665

Kód UT WoS článku

—

EID výsledku v databázi Scopus

—