On the role of Nb-related sites of an oxidized beta-TiNb alloy surface in its interaction with osteoblast-like MG-63 cells

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F13%3A00395053" target="_blank" >RIV/61388955:_____/13:00395053 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/67985823:_____/13:00395053

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.msec.2012.12.073" target="_blank" >http://dx.doi.org/10.1016/j.msec.2012.12.073</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.msec.2012.12.073" target="_blank" >10.1016/j.msec.2012.12.073</a>

Jazyk výsledku

angličtina

Název v původním jazyce

On the role of Nb-related sites of an oxidized beta-TiNb alloy surface in its interaction with osteoblast-like MG-63 cells

Popis výsledku v původním jazyce

beta-Stabilized titanium (Ti) alloys containing non-toxic elements, particularly niobium (Nb), are promising materials for the construction of bone implants. Their biocompatibility can be further increased by oxidation of their surface. Therefore, in this study, the adhesion, growth and viability of human osteoblast-like MG 63 cells in cultures on oxidized surfaces of a beta-TiNb alloy were investigated and compared with the cell behavior on thermally oxidized Ti, i.e. a metal commonly used for constructing bone implants. Four experimental groups of samples were prepared: Ti or TiNb samples annealed to 600 degrees C for 60 min in a stream of dry air, and Ti and TiNb samples treated in Piranha solution prior to annealing. We found that on all TiNb-basedsamples, the cell population densities on days 1,3 and 7 after seeding were higher than on the corresponding Ti-based samples. As revealed by XPS and Raman spectroscopy, and also by isoelectric point measurements, these results can be at

Název v anglickém jazyce

On the role of Nb-related sites of an oxidized beta-TiNb alloy surface in its interaction with osteoblast-like MG-63 cells

Popis výsledku anglicky

beta-Stabilized titanium (Ti) alloys containing non-toxic elements, particularly niobium (Nb), are promising materials for the construction of bone implants. Their biocompatibility can be further increased by oxidation of their surface. Therefore, in this study, the adhesion, growth and viability of human osteoblast-like MG 63 cells in cultures on oxidized surfaces of a beta-TiNb alloy were investigated and compared with the cell behavior on thermally oxidized Ti, i.e. a metal commonly used for constructing bone implants. Four experimental groups of samples were prepared: Ti or TiNb samples annealed to 600 degrees C for 60 min in a stream of dry air, and Ti and TiNb samples treated in Piranha solution prior to annealing. We found that on all TiNb-basedsamples, the cell population densities on days 1,3 and 7 after seeding were higher than on the corresponding Ti-based samples. As revealed by XPS and Raman spectroscopy, and also by isoelectric point measurements, these results can be at

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CF - Fyzikální chemie a teoretická chemie

OECD FORD obor

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Projekt

<a href="/cs/project/GAP108%2F10%2F1858" target="_blank" >GAP108/10/1858: Stabilita a biokompatibilita povrchu oxidické vrstvy jednofátové slitiny TiNb</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Materials Science & Engineering C-Materials for Biological Applications

ISSN

0928-4931

e-ISSN

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Svazek periodika

33

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

10

Strana od-do

1636-1645

Kód UT WoS článku

000315751600083

EID výsledku v databázi Scopus

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