On the role of Nb-related sites of an oxidized ?-TiNb alloy surface in its interaction with osteoblast-like MG-63 cells
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21220%2F13%3A00199456" target="_blank" >RIV/68407700:21220/13:00199456 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.1016/j.msec.2012.12.073" target="_blank" >http://dx.doi.org/10.1016/j.msec.2012.12.073</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.msec.2012.12.073" target="_blank" >10.1016/j.msec.2012.12.073</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
On the role of Nb-related sites of an oxidized ?-TiNb alloy surface in its interaction with osteoblast-like MG-63 cells
Popis výsledku v původním jazyce
?-stabilized titanium (Ti) alloys containing non-toxic elements, particularly niobium (Nb), are promising materials for the construction of bone implants. Their biocompatibility can be further increased by oxidation of their surface. Therefore, in this study, the adhesion, growth and viability of human osteoblast-like MG 63 cells in cultures on oxidized surfaces of a ?-TiNb alloy were investigated and compared with the cell behavior on thermally oxidized Ti, i.e. a metal commonly used for constructing bone implants. Four experimental groups of samples were prepared: Ti or TiNb samples annealed to 600°C for 60 min in a stream of dry air, and Ti and TiNb samples treated in Piranha solution prior to annealing. We found that on all TiNb-based samples, thecell population densities on days 1, 3 and 7 after seeding were higher than on the corresponding Ti-based samples. As revealed by XPS and Raman spectroscopy, and also by isoelectric point measurements, these results can be attributed to t
Název v anglickém jazyce
On the role of Nb-related sites of an oxidized ?-TiNb alloy surface in its interaction with osteoblast-like MG-63 cells
Popis výsledku anglicky
?-stabilized titanium (Ti) alloys containing non-toxic elements, particularly niobium (Nb), are promising materials for the construction of bone implants. Their biocompatibility can be further increased by oxidation of their surface. Therefore, in this study, the adhesion, growth and viability of human osteoblast-like MG 63 cells in cultures on oxidized surfaces of a ?-TiNb alloy were investigated and compared with the cell behavior on thermally oxidized Ti, i.e. a metal commonly used for constructing bone implants. Four experimental groups of samples were prepared: Ti or TiNb samples annealed to 600°C for 60 min in a stream of dry air, and Ti and TiNb samples treated in Piranha solution prior to annealing. We found that on all TiNb-based samples, thecell population densities on days 1, 3 and 7 after seeding were higher than on the corresponding Ti-based samples. As revealed by XPS and Raman spectroscopy, and also by isoelectric point measurements, these results can be attributed to t
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
JJ - Ostatní materiály
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/GAP108%2F10%2F1858" target="_blank" >GAP108/10/1858: Stabilita a biokompatibilita povrchu oxidické vrstvy jednofátové slitiny TiNb</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2013
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Materials Science and Engineering C, Biomimetic and Supramolecular Systems
ISSN
0928-4931
e-ISSN
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Svazek periodika
33
Číslo periodika v rámci svazku
3
Stát vydavatele periodika
NL - Nizozemsko
Počet stran výsledku
10
Strana od-do
1636-1645
Kód UT WoS článku
000315751600083
EID výsledku v databázi Scopus
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