SIFT-MS quantification of several breath biomarkers of inflammatory bowel disease, IBD: A detailed study of the ion chemistry

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F16%3A00462216" target="_blank" >RIV/61388955:_____/16:00462216 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11310/16:10332105

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.ijms.2015.12.007" target="_blank" >http://dx.doi.org/10.1016/j.ijms.2015.12.007</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ijms.2015.12.007" target="_blank" >10.1016/j.ijms.2015.12.007</a>

Jazyk výsledku

angličtina

Název v původním jazyce

SIFT-MS quantification of several breath biomarkers of inflammatory bowel disease, IBD: A detailed study of the ion chemistry

Popis výsledku v původním jazyce

Several compounds were previously identified as being present in modified concentrations in the breath of patients with inflammatory bowel diseases, IBD: 2-methylpentane, 1,3,5-triazine, trans-2-octene, cis-2-nonen-1-ol, 2-methylacetophenone, 1-heptene and 2-hexanone. A selected ion flow tube, SIFT, study has thus been carried out of the reactions of H3O+, NO+ and O2+radical dot with these volatile organic compounds. The rate constants and product ion branching ratios of the primary reactions including three body association rate constants, describing the rate of hydration, were obtained. The results of this study allow accurate SIFT-MS quantification of concentrations of these compounds in exhaled breath of IBD patients with the ultimate aim of establishing their use as non-invasive biomarkers of the disease activity.n

Název v anglickém jazyce

SIFT-MS quantification of several breath biomarkers of inflammatory bowel disease, IBD: A detailed study of the ion chemistry

Popis výsledku anglicky

Several compounds were previously identified as being present in modified concentrations in the breath of patients with inflammatory bowel diseases, IBD: 2-methylpentane, 1,3,5-triazine, trans-2-octene, cis-2-nonen-1-ol, 2-methylacetophenone, 1-heptene and 2-hexanone. A selected ion flow tube, SIFT, study has thus been carried out of the reactions of H3O+, NO+ and O2+radical dot with these volatile organic compounds. The rate constants and product ion branching ratios of the primary reactions including three body association rate constants, describing the rate of hydration, were obtained. The results of this study allow accurate SIFT-MS quantification of concentrations of these compounds in exhaled breath of IBD patients with the ultimate aim of establishing their use as non-invasive biomarkers of the disease activity.n

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CF - Fyzikální chemie a teoretická chemie

OECD FORD obor

—

Projekt

<a href="/cs/project/GA13-28882S" target="_blank" >GA13-28882S: Excitace, separace a fragmentace iontů v driftovém poli v SIFT-MS pro okamžitou selektivní kvantifikaci stopových plynů</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Mass Spectrometry

ISSN

1387-3806

e-ISSN

—

Svazek periodika

396

Číslo periodika v rámci svazku

FEB 2016

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

7

Strana od-do

35-41

Kód UT WoS článku

000370307500005

EID výsledku v databázi Scopus

2-s2.0-84956740983