Nanodiamonds as Intracellular Probes for Imaging in Biology and Medicine

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F14%3A00441403" target="_blank" >RIV/61388963:_____/14:00441403 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1007/978-94-017-8896-0_18" target="_blank" >http://dx.doi.org/10.1007/978-94-017-8896-0_18</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/978-94-017-8896-0_18" target="_blank" >10.1007/978-94-017-8896-0_18</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Nanodiamonds as Intracellular Probes for Imaging in Biology and Medicine

Popis výsledku v původním jazyce

In recent years, diamond nanoparticles have received a great deal of attention due to their unique photophysical and biological properties. Nanodiamonds (NDs) show low toxicity and are considered to be a highly biocompatible carbon nanomaterial useful ina wide range of applications. Thanks to their ability to accommodate nitrogen-vacancy (N-V) color centers, NDs are a prime example of non-photobleachable fluorescent labels and nanosensors. Here, we present a survey of ND applications in biology and medicine with an emphasis on bioimaging. We focus on distinguishing the properties of detonation NDs and high-pressure high-temperature (HPHT) NDs and describing their physicochemical properties, structure and possible modifications by small molecules and biomolecules. We summarize and critically evaluate in vitro and in vivo data on ND toxicity and biocompatibility, cellular internalization, localization and targeting by surface-attached ligands. We discuss current achievements in bioimagi

Název v anglickém jazyce

Nanodiamonds as Intracellular Probes for Imaging in Biology and Medicine

Popis výsledku anglicky

In recent years, diamond nanoparticles have received a great deal of attention due to their unique photophysical and biological properties. Nanodiamonds (NDs) show low toxicity and are considered to be a highly biocompatible carbon nanomaterial useful ina wide range of applications. Thanks to their ability to accommodate nitrogen-vacancy (N-V) color centers, NDs are a prime example of non-photobleachable fluorescent labels and nanosensors. Here, we present a survey of ND applications in biology and medicine with an emphasis on bioimaging. We focus on distinguishing the properties of detonation NDs and high-pressure high-temperature (HPHT) NDs and describing their physicochemical properties, structure and possible modifications by small molecules and biomolecules. We summarize and critically evaluate in vitro and in vivo data on ND toxicity and biocompatibility, cellular internalization, localization and targeting by surface-attached ligands. We discuss current achievements in bioimagi

Druh

C - Kapitola v odborné knize

CEP obor

EI - Biotechnologie a bionika

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Intracellular Delivery II: Fundamentals and Applications

ISBN

978-94-017-8895-3

Počet stran výsledku

39

Strana od-do

363-401

Počet stran knihy

479

Název nakladatele

Springer

Místo vydání

Dordrecht

Kód UT WoS kapitoly

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