Applications of capillary electromigration methods for separation and analysis of proteins (2017-mid 2021) - A review

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F22%3A00558438" target="_blank" >RIV/61388963:_____/22:00558438 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1016/j.aca.2022.339447" target="_blank" >https://doi.org/10.1016/j.aca.2022.339447</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.aca.2022.339447" target="_blank" >10.1016/j.aca.2022.339447</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Applications of capillary electromigration methods for separation and analysis of proteins (2017-mid 2021) - A review

Popis výsledku v původním jazyce

This paper provides a detailed overview of relevant developments in separation and analysis of proteins by capillary electromigration (CE) methods in the period 2017-mid 2021. The presented topics embrace sample preparation, suppression of protein sorption, control of electroosmotic flow, separations of proteins by the particular CE methods and protein identification and quantification by various detection techniques. To illustrate the wide usability of CE methods for protein analysis, the paper shows several novel applications of CE methods, such as quality control and characterization of protein biopharmaceuticals, determination of proteins in complex biomatrices, investigation of posttranslational modification, peptide mapping, interactions of proteins with other (bio)molecules and determination of their physicochemical and biochemical characteristics.

Název v anglickém jazyce

Applications of capillary electromigration methods for separation and analysis of proteins (2017-mid 2021) - A review

Popis výsledku anglicky

This paper provides a detailed overview of relevant developments in separation and analysis of proteins by capillary electromigration (CE) methods in the period 2017-mid 2021. The presented topics embrace sample preparation, suppression of protein sorption, control of electroosmotic flow, separations of proteins by the particular CE methods and protein identification and quantification by various detection techniques. To illustrate the wide usability of CE methods for protein analysis, the paper shows several novel applications of CE methods, such as quality control and characterization of protein biopharmaceuticals, determination of proteins in complex biomatrices, investigation of posttranslational modification, peptide mapping, interactions of proteins with other (bio)molecules and determination of their physicochemical and biochemical characteristics.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10406 - Analytical chemistry

Projekt

<a href="/cs/project/GA20-03899S" target="_blank" >GA20-03899S: Afinitní kapilární elektrokinetické metody pro selektivní analýzu biopolymerů a metabolitů a pro studium jejich interakcí</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Analytica Chimica Acta

ISSN

0003-2670

e-ISSN

1873-4324

Svazek periodika

1209

Číslo periodika v rámci svazku

May

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

29

Strana od-do

339447

Kód UT WoS článku

000802192800004

EID výsledku v databázi Scopus

2-s2.0-85123869892