From the outer ear to the nerve: A complete computer model of the peripheral auditory system

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F23%3A00577750" target="_blank" >RIV/61388963:_____/23:00577750 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1016/j.heares.2023.108900" target="_blank" >https://doi.org/10.1016/j.heares.2023.108900</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.heares.2023.108900" target="_blank" >10.1016/j.heares.2023.108900</a>

Jazyk výsledku

angličtina

Název v původním jazyce

From the outer ear to the nerve: A complete computer model of the peripheral auditory system

Popis výsledku v původním jazyce

Computer models of the individual components of the peripheral auditory system – the outer, middle, and inner ears and the auditory nerve – have been developed in the past, with varying level of detail, breadth, and faithfulness of the underlying parameters. Building on previous work, we advance the modeling of the ear by presenting a complete, physiologically justified, bottom-up computer model based on up-to-date experimental data that integrates all of these parts together seamlessly. The detailed bottom-up design of the present model allows for the investigation of partial hearing mechanisms and their defects, including genetic, molecular, and microscopic factors. Also, thanks to the completeness of the model, one can study microscopic effects in the context of their implications on hearing as a whole, enabling the correlation with neural recordings and non-invasive psychoacoustic methods. Such a model is instrumental for advancing quantitative understanding of the mechanism of hearing, for investigating various forms of hearing impairment, as well as for devising next generation hearing aids and cochlear implants.

Název v anglickém jazyce

From the outer ear to the nerve: A complete computer model of the peripheral auditory system

Popis výsledku anglicky

Computer models of the individual components of the peripheral auditory system – the outer, middle, and inner ears and the auditory nerve – have been developed in the past, with varying level of detail, breadth, and faithfulness of the underlying parameters. Building on previous work, we advance the modeling of the ear by presenting a complete, physiologically justified, bottom-up computer model based on up-to-date experimental data that integrates all of these parts together seamlessly. The detailed bottom-up design of the present model allows for the investigation of partial hearing mechanisms and their defects, including genetic, molecular, and microscopic factors. Also, thanks to the completeness of the model, one can study microscopic effects in the context of their implications on hearing as a whole, enabling the correlation with neural recordings and non-invasive psychoacoustic methods. Such a model is instrumental for advancing quantitative understanding of the mechanism of hearing, for investigating various forms of hearing impairment, as well as for devising next generation hearing aids and cochlear implants.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Hearing Research

ISSN

0378-5955

e-ISSN

1878-5891

Svazek periodika

440

Číslo periodika v rámci svazku

December

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

23

Strana od-do

108900

Kód UT WoS článku

001110998000001

EID výsledku v databázi Scopus

2-s2.0-85175698417