Lipidomics of Pro-inflammatory and Anti-inflammatory Macrophages

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F24%3A00598111" target="_blank" >RIV/61388963:_____/24:00598111 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Lipidomics of Pro-inflammatory and Anti-inflammatory Macrophages

Popis výsledku v původním jazyce

An increasing incidence of cardiovascular diseases in the developed countries population is obvious. Factors contributing to their development are obesity and pro-inflammatory processes occurring in the adipose tissue. Macrophages, cells of the non-specific immune system, are also an important component of adipose tissue. Macrophages can be classified as pro-inflammatory and anti-inflammatory. They play a significant role in biological processes. For a better understanding of these phenomena, it is necessary to analyze the lipidome of macrophages of both mentioned groups. We optimized the LC-MS method for the lipidomic analysis of macrophages and found the lipidome differences.

Název v anglickém jazyce

Lipidomics of Pro-inflammatory and Anti-inflammatory Macrophages

Popis výsledku anglicky

An increasing incidence of cardiovascular diseases in the developed countries population is obvious. Factors contributing to their development are obesity and pro-inflammatory processes occurring in the adipose tissue. Macrophages, cells of the non-specific immune system, are also an important component of adipose tissue. Macrophages can be classified as pro-inflammatory and anti-inflammatory. They play a significant role in biological processes. For a better understanding of these phenomena, it is necessary to analyze the lipidome of macrophages of both mentioned groups. We optimized the LC-MS method for the lipidomic analysis of macrophages and found the lipidome differences.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10406 - Analytical chemistry

Projekt

<a href="/cs/project/LX22NPO5104" target="_blank" >LX22NPO5104: Národní institut pro výzkum metabolických a kardiovaskulárních onemocnění</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů