Deregulation of expression of virulence factors in fur mutants of Pseudomonas aeruginosa

Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F10%3A00357396" target="_blank" >RIV/61388971:_____/10:00357396 - isvavai.cz</a>
Výsledek na webu
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DOI - Digital Object Identifier
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Jazyk výsledku
angličtina
Název v původním jazyce
Deregulation of expression of virulence factors in fur mutants of Pseudomonas aeruginosa
Popis výsledku v původním jazyce
Increased production of the virulent factors was found in the fur mutant strains of Pseudomonas aeruginosa FPA12 and FF13 even under conditions of their full repression by FeIII. The mutants overproduce specific receptors for pyoverdine (FpvA) and pyochelin (FptA) in iron-deplete medium. Upon FeIII supplementation into the medium (60?M FeCl3) the Fur phenotype of fur mutants was studied. Transcription profiling of the fur mutant strain FPA12 in response of iron was performed with focus on the expressionof Fur-regulated genes coding for virulence factors
Název v anglickém jazyce
Deregulation of expression of virulence factors in fur mutants of Pseudomonas aeruginosa
Popis výsledku anglicky
Increased production of the virulent factors was found in the fur mutant strains of Pseudomonas aeruginosa FPA12 and FF13 even under conditions of their full repression by FeIII. The mutants overproduce specific receptors for pyoverdine (FpvA) and pyochelin (FptA) in iron-deplete medium. Upon FeIII supplementation into the medium (60?M FeCl3) the Fur phenotype of fur mutants was studied. Transcription profiling of the fur mutant strain FPA12 in response of iron was performed with focus on the expressionof Fur-regulated genes coding for virulence factors

Rok uplatnění
2010
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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