Fungal microsomes in a biotransformation perspective: protein nature of membrane-associated reactions
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F13%3A00422882" target="_blank" >RIV/61388971:_____/13:00422882 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.1007/s00253-013-5347-2" target="_blank" >http://dx.doi.org/10.1007/s00253-013-5347-2</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00253-013-5347-2" target="_blank" >10.1007/s00253-013-5347-2</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Fungal microsomes in a biotransformation perspective: protein nature of membrane-associated reactions
Popis výsledku v původním jazyce
Microsomal fraction of fungal cells grabs the attention of many researchers for it contains enzymes that play a role in biotechnologically relevant processes. Microsomal enzymes, namely, CYP450s, were shown to metabolize a wide range of xenobiotic compounds, including PAHs, PCBs, dioxins, and endocrine disruptors, and take part in other fungal biotransformation reactions. However, little is known about the nature and regulation of these membrane-associated reactions. Advanced proteomic and post-genomictechniques make it possible to identify larger numbers of microsomal proteins and thus add to a deeper study of fungal intracellular processes. In this work, proteins that were identified through a shotgun proteomic approach in fungal microsomes under various culture conditions are reviewed. However, further research is still needed to fully understand the role of microsomes in fungal biodegradation and biotransformation reactions
Název v anglickém jazyce
Fungal microsomes in a biotransformation perspective: protein nature of membrane-associated reactions
Popis výsledku anglicky
Microsomal fraction of fungal cells grabs the attention of many researchers for it contains enzymes that play a role in biotechnologically relevant processes. Microsomal enzymes, namely, CYP450s, were shown to metabolize a wide range of xenobiotic compounds, including PAHs, PCBs, dioxins, and endocrine disruptors, and take part in other fungal biotransformation reactions. However, little is known about the nature and regulation of these membrane-associated reactions. Advanced proteomic and post-genomictechniques make it possible to identify larger numbers of microsomal proteins and thus add to a deeper study of fungal intracellular processes. In this work, proteins that were identified through a shotgun proteomic approach in fungal microsomes under various culture conditions are reviewed. However, further research is still needed to fully understand the role of microsomes in fungal biodegradation and biotransformation reactions
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
EE - Mikrobiologie, virologie
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/TE01020218" target="_blank" >TE01020218: Ekologicky šetrné nanotechnologie a biotechnologie pro čištění vod a půd</a><br>
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2013
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Applied Microbiology and Biotechnology
ISSN
0175-7598
e-ISSN
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Svazek periodika
97
Číslo periodika v rámci svazku
24
Stát vydavatele periodika
DE - Spolková republika Německo
Počet stran výsledku
11
Strana od-do
10263-10273
Kód UT WoS článku
000327495000003
EID výsledku v databázi Scopus
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