Biotransformation of Natural Products and Phytochemicals: Metabolites, Their Preparation, and Properties

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F23%3A00572413" target="_blank" >RIV/61388971:_____/23:00572413 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.mdpi.com/1422-0067/24/9/8030" target="_blank" >https://www.mdpi.com/1422-0067/24/9/8030</a>

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Biotransformation of Natural Products and Phytochemicals: Metabolites, Their Preparation, and Properties

Popis výsledku v původním jazyce

The term “biotransformation” refers to the process by which various compounds are biocatalyzed and enzymatically modified, as well as the metabolic changes that occur in organisms as a result of exposure to xenobiotics. This Special Issue focuses on both these connotations of biotransformation and specifically on the biotransformations of natural products and phytochemicals. Metabolites of xenobiotics may have different biological and biophysical properties compared to their parent compounds, which can result in inactivation, toxication, or al‐ teration in activity. In contrast, phytochemicals and other natural products are gaining increasing attention for their significant benefits in preventing and managing chronic dis‐ eases. However, these compounds often suffer from low bioavailability and extensive me‐ tabolism, with their metabolites being responsible for their biological effects.

Název v anglickém jazyce

Biotransformation of Natural Products and Phytochemicals: Metabolites, Their Preparation, and Properties

Popis výsledku anglicky

The term “biotransformation” refers to the process by which various compounds are biocatalyzed and enzymatically modified, as well as the metabolic changes that occur in organisms as a result of exposure to xenobiotics. This Special Issue focuses on both these connotations of biotransformation and specifically on the biotransformations of natural products and phytochemicals. Metabolites of xenobiotics may have different biological and biophysical properties compared to their parent compounds, which can result in inactivation, toxication, or al‐ teration in activity. In contrast, phytochemicals and other natural products are gaining increasing attention for their significant benefits in preventing and managing chronic dis‐ eases. However, these compounds often suffer from low bioavailability and extensive me‐ tabolism, with their metabolites being responsible for their biological effects.

Druh

O - Ostatní výsledky

CEP obor

—

OECD FORD obor

30104 - Pharmacology and pharmacy

Projekt

<a href="/cs/project/GA23-04654S" target="_blank" >GA23-04654S: Chemoenzymatická příprava a biologická aktivita metabolitů polyfenolových sloučenin z potravy</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů