Peripheral Modulators of Appetite in Eating Disorders

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F23%3A00574042" target="_blank" >RIV/61388971:_____/23:00574042 - isvavai.cz</a>

Výsledek na webu

<a href="https://link.springer.com/referenceworkentry/10.1007/978-3-030-97416-9_113-1" target="_blank" >https://link.springer.com/referenceworkentry/10.1007/978-3-030-97416-9_113-1</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/978-3-030-97416-9_113-1" target="_blank" >10.1007/978-3-030-97416-9_113-1</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Peripheral Modulators of Appetite in Eating Disorders

Popis výsledku v původním jazyce

Regulation of food intake is complex, with many peripheral and central inputs. The goal of these inputs is homeostatic maintenance of stable weight and optimal nutrient supplies. Homeostatic regulation includes central mechanisms in the hypothalamus and peripheral short- and long-term mechanisms, mediated mainly by gastrointestinal and adipose tissue peptides. Appetite and feeding regulatingnfactors can be described as orexigenic (appetite and feeding-enhancing) or anorexigenic (appetite and feeding-reducing). Orexigenic factors involve peripheral ghrelin and the centrally acting NPY/AgRP system. Anorexigenic factors include gastrointestinal peptides, the adipose tissue hormone leptin, and the centrally acting melanocortin system. In addition to homeostatic regulation, hedonic and cognitive feedback neurocircuits influence feeding and appetite, and their dysfunction plays an essential role in the onset and maintenance ofnseveral psychiatric diseases, mainly eating disorders. In-depth knowledge of changes in brain connectivity and central and peripheral mechanisms of food intake regulation is crucial for understanding the pathogenesis of eating disorders, obesity, and comorbidities.n

Název v anglickém jazyce

Peripheral Modulators of Appetite in Eating Disorders

Popis výsledku anglicky

Regulation of food intake is complex, with many peripheral and central inputs. The goal of these inputs is homeostatic maintenance of stable weight and optimal nutrient supplies. Homeostatic regulation includes central mechanisms in the hypothalamus and peripheral short- and long-term mechanisms, mediated mainly by gastrointestinal and adipose tissue peptides. Appetite and feeding regulatingnfactors can be described as orexigenic (appetite and feeding-enhancing) or anorexigenic (appetite and feeding-reducing). Orexigenic factors involve peripheral ghrelin and the centrally acting NPY/AgRP system. Anorexigenic factors include gastrointestinal peptides, the adipose tissue hormone leptin, and the centrally acting melanocortin system. In addition to homeostatic regulation, hedonic and cognitive feedback neurocircuits influence feeding and appetite, and their dysfunction plays an essential role in the onset and maintenance ofnseveral psychiatric diseases, mainly eating disorders. In-depth knowledge of changes in brain connectivity and central and peripheral mechanisms of food intake regulation is crucial for understanding the pathogenesis of eating disorders, obesity, and comorbidities.n

Druh

C - Kapitola v odborné knize

CEP obor

—

OECD FORD obor

30215 - Psychiatry

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Eating Disorders

ISBN

978-3-030-97416-9

Počet stran výsledku

20

Strana od-do

—

Počet stran knihy

1161

Název nakladatele

Springer

Místo vydání

Cham

Kód UT WoS kapitoly

—