Role of sigma factors of RNA polymerase in bacterial physiology, volume II

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Role of sigma factors of RNA polymerase in bacterial physiology, volume II

Popis výsledku v původním jazyce

Gene expression in bacteria is controlled by three main types of protein regulators: DNA-binding transcriptional regulators, two-component systems, and sigma (σ) factors of RNA polymerase. Since RNA polymerase is essential for transcription, sigma factors, as its subunits are involved in the control of each gene. In many cases, the main regulators control the expression of a gene cooperatively. Bacteria contain between two and more than 60 different σ factors, depending on the species. One of these, usually called σ A, is responsible for the transcription of most housekeeping genes, while the others are alternative. A large number of σ factors induced in most bacteria by various stresses belong to group 4 of sigma factors, called extracytoplasmic function sigma factors (ECF σ). All four articles in this Research Topic are dedicated to this type of σ. Two articles describe original research, and two others are reviews. Three contributions deal with gram-positive bacteria (Corynebacterium glutamicum, Mycobacterium tuberculosis, and Listeria monocytogenes) and one with a gram-negative bacterium (Burkholderia sp.)

Název v anglickém jazyce

Role of sigma factors of RNA polymerase in bacterial physiology, volume II

Popis výsledku anglicky

Gene expression in bacteria is controlled by three main types of protein regulators: DNA-binding transcriptional regulators, two-component systems, and sigma (σ) factors of RNA polymerase. Since RNA polymerase is essential for transcription, sigma factors, as its subunits are involved in the control of each gene. In many cases, the main regulators control the expression of a gene cooperatively. Bacteria contain between two and more than 60 different σ factors, depending on the species. One of these, usually called σ A, is responsible for the transcription of most housekeeping genes, while the others are alternative. A large number of σ factors induced in most bacteria by various stresses belong to group 4 of sigma factors, called extracytoplasmic function sigma factors (ECF σ). All four articles in this Research Topic are dedicated to this type of σ. Two articles describe original research, and two others are reviews. Three contributions deal with gram-positive bacteria (Corynebacterium glutamicum, Mycobacterium tuberculosis, and Listeria monocytogenes) and one with a gram-negative bacterium (Burkholderia sp.)

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10606 - Microbiology

Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů