Low-molecular-weight chitosans: Preparation and characterization

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F11%3A00361593" target="_blank" >RIV/61389013:_____/11:00361593 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/67985904:_____/11:00361593

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.carbpol.2011.04.073" target="_blank" >http://dx.doi.org/10.1016/j.carbpol.2011.04.073</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.carbpol.2011.04.073" target="_blank" >10.1016/j.carbpol.2011.04.073</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Low-molecular-weight chitosans: Preparation and characterization

Popis výsledku v původním jazyce

The chitosan depolymerization products prepared by enzymatic hydrolysis, oxidative reaction or microwave irradiation were characterized by FT-IR, MALDI TOF MS, solid state 13C CP/MAS NMR and GPC. Enzymatic hydrolysis resulted in two fractions of low-molecular-weight (LMW) chitosans with Mw 34 kDa (3.9 wt%) and 14.6 kDa (8.5 wt%). In the oxidative reaction at the hydrogen peroxide and acetic acid molar ratio equal to 1.7, two LMW chitosans with Mw 9 and 10 kDa (the deacetylation degree 69% and 94%, respectively) were isolated with the total yield 86 wt%. In microwave irradiation, the Mw of chitosan (175.5 kDa) decreased at most in two times. Two chitosan fractions with Mw 80 and 120 kDa (total yield 70 wt%) were obtained. In all cases, LMW chitosans served as fortifiers for chitosan oligomers, which were retained with the former through multiple hydrogen bonds. Their content in LMW chitosans was roughly 20?30 wt%.

Název v anglickém jazyce

Low-molecular-weight chitosans: Preparation and characterization

Popis výsledku anglicky

The chitosan depolymerization products prepared by enzymatic hydrolysis, oxidative reaction or microwave irradiation were characterized by FT-IR, MALDI TOF MS, solid state 13C CP/MAS NMR and GPC. Enzymatic hydrolysis resulted in two fractions of low-molecular-weight (LMW) chitosans with Mw 34 kDa (3.9 wt%) and 14.6 kDa (8.5 wt%). In the oxidative reaction at the hydrogen peroxide and acetic acid molar ratio equal to 1.7, two LMW chitosans with Mw 9 and 10 kDa (the deacetylation degree 69% and 94%, respectively) were isolated with the total yield 86 wt%. In microwave irradiation, the Mw of chitosan (175.5 kDa) decreased at most in two times. Two chitosan fractions with Mw 80 and 120 kDa (total yield 70 wt%) were obtained. In all cases, LMW chitosans served as fortifiers for chitosan oligomers, which were retained with the former through multiple hydrogen bonds. Their content in LMW chitosans was roughly 20?30 wt%.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

ED - Fyziologie

OECD FORD obor

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Projekt

<a href="/cs/project/GA525%2F08%2F0803" target="_blank" >GA525/08/0803: Působení chitooligosacharidů v tračníku člověka</a><br>

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Carbohydrate Polymers

ISSN

0144-8617

e-ISSN

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Svazek periodika

86

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

5

Strana od-do

1077-1081

Kód UT WoS článku

000294187400094

EID výsledku v databázi Scopus

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