Controlled growth of protein resistant PHEMA brushes via S-RAFT polymerization

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F13%3A00399476" target="_blank" >RIV/61389013:_____/13:00399476 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1039/c3tb20880j" target="_blank" >http://dx.doi.org/10.1039/c3tb20880j</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1039/c3tb20880j" target="_blank" >10.1039/c3tb20880j</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Controlled growth of protein resistant PHEMA brushes via S-RAFT polymerization

Popis výsledku v původním jazyce

The reversible addition?fragmentation chain transfer polymerization of 2-hydroxyethyl methacrylate (HEMA) from surfaces (S-RAFT) using an R-group-attached chain transfer agent (CTA) is presented. The approach was exploited for the efficient preparation of well-defined PHEMA brushes of up to 50 nm thickness in a controlled fashion without using any cytotoxic catalyst. The chemical composition, morphology and wettability of the samples were assessed by X-ray photoelectron spectroscopy, atomic force microscopy and water contact angle measurements, while the growth kinetics were studied by monitoring the dry thickness via spectroscopic ellipsometry. The mechanism and kinetics of the RAFT polymerization on the surface ? in the presence of a sacrificial CTAand of solvent mixtures with different polarities ? were investigated. A marked effect of the concentration of the sacrificial CTA on the kinetics was observed. Importantly ? and for the first time ? the living PHEMA brushes were exploite

Název v anglickém jazyce

Controlled growth of protein resistant PHEMA brushes via S-RAFT polymerization

Popis výsledku anglicky

The reversible addition?fragmentation chain transfer polymerization of 2-hydroxyethyl methacrylate (HEMA) from surfaces (S-RAFT) using an R-group-attached chain transfer agent (CTA) is presented. The approach was exploited for the efficient preparation of well-defined PHEMA brushes of up to 50 nm thickness in a controlled fashion without using any cytotoxic catalyst. The chemical composition, morphology and wettability of the samples were assessed by X-ray photoelectron spectroscopy, atomic force microscopy and water contact angle measurements, while the growth kinetics were studied by monitoring the dry thickness via spectroscopic ellipsometry. The mechanism and kinetics of the RAFT polymerization on the surface ? in the presence of a sacrificial CTAand of solvent mixtures with different polarities ? were investigated. A marked effect of the concentration of the sacrificial CTA on the kinetics was observed. Importantly ? and for the first time ? the living PHEMA brushes were exploite

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CD - Makromolekulární chemie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Materials Chemistry B

ISSN

2050-750X

e-ISSN

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Svazek periodika

1

Číslo periodika v rámci svazku

44

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

8

Strana od-do

6027-6034

Kód UT WoS článku

000326244900003

EID výsledku v databázi Scopus

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